Tilby MJ - Search Results

1

gammaH2AX foci form preferentially in euchromatin after ionising-radiation.

Cowell IG, Sunter NJ, Singh PB, Austin CA, Durkacz BW, Tilby MJ. Cowell IG, et al. Among authors: tilby mj. PLoS One. 2007 Oct 24;2(10):e1057. doi: 10.1371/journal.pone.0001057. PLoS One. 2007. PMID: 17957241 Free PMC article.

2

A novel DNA-dependent protein kinase inhibitor, NU7026, potentiates the cytotoxicity of topoisomerase II poisons used in the treatment of leukemia.

Willmore E, de Caux S, Sunter NJ, Tilby MJ, Jackson GH, Austin CA, Durkacz BW. Willmore E, et al. Among authors: tilby mj. Blood. 2004 Jun 15;103(12):4659-65. doi: 10.1182/blood-2003-07-2527. Epub 2004 Mar 9. Blood. 2004. PMID: 15010369 Free article.

3

Sensitization of breast carcinoma cells to ionizing radiation by small molecule inhibitors of DNA-dependent protein kinase and ataxia telangiectsia mutated.

Cowell IG, Durkacz BW, Tilby MJ. Cowell IG, et al. Among authors: tilby mj. Biochem Pharmacol. 2005 Dec 19;71(1-2):13-20. doi: 10.1016/j.bcp.2005.09.029. Epub 2005 Nov 15. Biochem Pharmacol. 2005. PMID: 16293233

4

An overview of the visualisation and quantitation of low and high MW DNA adducts using the trapped in agarose DNA immunostaining (TARDIS) assay.

Cowell IG, Tilby MJ, Austin CA. Cowell IG, et al. Among authors: tilby mj. Mutagenesis. 2011 Mar;26(2):253-60. doi: 10.1093/mutage/geq094. Epub 2010 Nov 10. Mutagenesis. 2011. PMID: 21068206 Review.

5

Effect of phenazine compounds XR11576 and XR5944 on DNA topoisomerases.

Jobson AG, Willmore E, Tilby MJ, Mistry P, Charlton P, Austin CA. Jobson AG, et al. Among authors: tilby mj. Cancer Chemother Pharmacol. 2009 Apr;63(5):889-901. doi: 10.1007/s00280-008-0812-9. Epub 2008 Aug 5. Cancer Chemother Pharmacol. 2009. PMID: 18679685

6

Formation and longevity of idarubicin-induced DNA topoisomerase II cleavable complexes in K562 human leukaemia cells.

Willmore E, Errington F, Tilby MJ, Austin CA. Willmore E, et al. Among authors: tilby mj. Biochem Pharmacol. 2002 May 15;63(10):1807-15. doi: 10.1016/s0006-2952(02)00920-6. Biochem Pharmacol. 2002. PMID: 12034365

7

Differences in the longevity of topo IIalpha and topo IIbeta drug-stabilized cleavable complexes and the relationship to drug sensitivity.

Errington F, Willmore E, Leontiou C, Tilby MJ, Austin CA. Errington F, et al. Among authors: tilby mj. Cancer Chemother Pharmacol. 2004 Feb;53(2):155-62. doi: 10.1007/s00280-003-0701-1. Epub 2003 Sep 23. Cancer Chemother Pharmacol. 2004. PMID: 14504921

8

Etoposide targets topoisomerase IIalpha and IIbeta in leukemic cells: isoform-specific cleavable complexes visualized and quantified in situ by a novel immunofluorescence technique.

Willmore E, Frank AJ, Padget K, Tilby MJ, Austin CA. Willmore E, et al. Among authors: tilby mj. Mol Pharmacol. 1998 Jul;54(1):78-85. doi: 10.1124/mol.54.1.78. Mol Pharmacol. 1998. PMID: 9658192

9

Camptothecin-stabilised topoisomerase I-DNA complexes in leukaemia cells visualised and quantified in situ by the TARDIS assay (trapped in agarose DNA immunostaining).

Padget K, Carr R, Pearson AD, Tilby MJ, Austin CA. Padget K, et al. Among authors: tilby mj. Biochem Pharmacol. 2000 Mar 15;59(6):629-38. doi: 10.1016/s0006-2952(99)00372-x. Biochem Pharmacol. 2000. PMID: 10677579

10

An investigation into the formation of N- [2-(dimethylamino)ethyl]acridine-4-carboxamide (DACA) and 6-[2-(dimethylamino)ethylamino]- 3-hydroxy-7H-indeno[2, 1-C]quinolin-7-one dihydrochloride (TAS-103) stabilised DNA topoisomerase I and II cleavable complexes in human leukaemia cells.

Padget K, Stewart A, Charlton P, Tilby MJ, Austin CA. Padget K, et al. Among authors: tilby mj. Biochem Pharmacol. 2000 Sep 15;60(6):817-21. doi: 10.1016/s0006-2952(00)00402-0. Biochem Pharmacol. 2000. PMID: 10930536

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