Kumar A - Search Results

1

Cytotoxic and apoptotic activities of novel amino analogues of boswellic acids.

Shah BA, Kumar A, Gupta P, Sharma M, Sethi VK, Saxena AK, Singh J, Qazi GN, Taneja SC. Shah BA, et al. Among authors: kumar a. Bioorg Med Chem Lett. 2007 Dec 1;17(23):6411-6. doi: 10.1016/j.bmcl.2007.10.011. Epub 2007 Oct 10. Bioorg Med Chem Lett. 2007. PMID: 17950603

2

A triterpenediol from Boswellia serrata induces apoptosis through both the intrinsic and extrinsic apoptotic pathways in human leukemia HL-60 cells.

Bhushan S, Kumar A, Malik F, Andotra SS, Sethi VK, Kaur IP, Taneja SC, Qazi GN, Singh J. Bhushan S, et al. Among authors: kumar a. Apoptosis. 2007 Oct;12(10):1911-26. doi: 10.1007/s10495-007-0105-5. Apoptosis. 2007. PMID: 17636381

3

Reactive oxygen species generation and mitochondrial dysfunction in the apoptotic cell death of human myeloid leukemia HL-60 cells by a dietary compound withaferin A with concomitant protection by N-acetyl cysteine.

Malik F, Kumar A, Bhushan S, Khan S, Bhatia A, Suri KA, Qazi GN, Singh J. Malik F, et al. Among authors: kumar a. Apoptosis. 2007 Nov;12(11):2115-33. doi: 10.1007/s10495-007-0129-x. Apoptosis. 2007. PMID: 17874299

4

An essential oil and its major constituent isointermedeol induce apoptosis by increased expression of mitochondrial cytochrome c and apical death receptors in human leukaemia HL-60 cells.

Kumar A, Malik F, Bhushan S, Sethi VK, Shahi AK, Kaur J, Taneja SC, Qazi GN, Singh J. Kumar A, et al. Chem Biol Interact. 2008 Feb 15;171(3):332-47. doi: 10.1016/j.cbi.2007.10.003. Epub 2007 Oct 24. Chem Biol Interact. 2008. PMID: 18070620

5

Immune modulation and apoptosis induction: Two sides of antitumoural activity of a standardised herbal formulation of Withania somnifera.

Malik F, Kumar A, Bhushan S, Mondhe DM, Pal HC, Sharma R, Khajuria A, Singh S, Singh G, Saxena AK, Suri KA, Qazi GN, Singh J. Malik F, et al. Among authors: kumar a. Eur J Cancer. 2009 May;45(8):1494-509. doi: 10.1016/j.ejca.2009.01.034. Epub 2009 Mar 5. Eur J Cancer. 2009. PMID: 19269163

6

Structure-activity relationship (SAR) of parthenin analogues with pro-apoptotic activity: Development of novel anti-cancer leads.

Shah BA, Kaur R, Gupta P, Kumar A, Sethi VK, Andotra SS, Singh J, Saxena AK, Taneja SC. Shah BA, et al. Among authors: kumar a. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4394-8. doi: 10.1016/j.bmcl.2009.05.089. Epub 2009 May 28. Bioorg Med Chem Lett. 2009. PMID: 19501509

7

Activation of p53/p21/PUMA alliance and disruption of PI-3/Akt in multimodal targeting of apoptotic signaling cascades in cervical cancer cells by a pentacyclic triterpenediol from Boswellia serrata.

Bhushan S, Malik F, Kumar A, Isher HK, Kaur IP, Taneja SC, Singh J. Bhushan S, et al. Among authors: kumar a. Mol Carcinog. 2009 Dec;48(12):1093-108. doi: 10.1002/mc.20559. Mol Carcinog. 2009. PMID: 19544329

8

A novel parthenin analog exhibits anti-cancer activity: activation of apoptotic signaling events through robust NO formation in human leukemia HL-60 cells.

Kumar A, Malik F, Bhushan S, Shah BA, Taneja SC, Pal HC, Wani ZA, Mondhe DM, Kaur J, Singh J. Kumar A, et al. Chem Biol Interact. 2011 Sep 30;193(3):204-15. doi: 10.1016/j.cbi.2011.06.006. Epub 2011 Jun 29. Chem Biol Interact. 2011. PMID: 21741372

9

A novel cyano derivative of 11-keto-β-boswellic acid causes apoptotic death by disrupting PI3K/AKT/Hsp-90 cascade, mitochondrial integrity, and other cell survival signaling events in HL-60 cells.

Khan S, Kaur R, Shah BA, Malik F, Kumar A, Bhushan S, Jain SK, Taneja SC, Singh J. Khan S, et al. Among authors: kumar a. Mol Carcinog. 2012 Sep;51(9):679-95. doi: 10.1002/mc.20821. Epub 2011 Jul 12. Mol Carcinog. 2012. PMID: 21751262

10

Acyl derivatives of boswellic acids as inhibitors of NF-κB and STATs.

Kumar A, Shah BA, Singh S, Hamid A, Singh SK, Sethi VK, Saxena AK, Singh J, Taneja SC. Kumar A, et al. Bioorg Med Chem Lett. 2012 Jan 1;22(1):431-5. doi: 10.1016/j.bmcl.2011.10.112. Epub 2011 Nov 9. Bioorg Med Chem Lett. 2012. PMID: 22123322

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