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Page 1
Tryptophan supports interaction of transmembrane helices.
Ridder A, Skupjen P, Unterreitmeier S, Langosch D. Ridder A, et al. Among authors: unterreitmeier s. J Mol Biol. 2005 Dec 9;354(4):894-902. doi: 10.1016/j.jmb.2005.09.084. Epub 2005 Oct 21. J Mol Biol. 2005. PMID: 16280130
Amyloid beta 42 peptide (Abeta42)-lowering compounds directly bind to Abeta and interfere with amyloid precursor protein (APP) transmembrane dimerization.
Richter L, Munter LM, Ness J, Hildebrand PW, Dasari M, Unterreitmeier S, Bulic B, Beyermann M, Gust R, Reif B, Weggen S, Langosch D, Multhaup G. Richter L, et al. Among authors: unterreitmeier s. Proc Natl Acad Sci U S A. 2010 Aug 17;107(33):14597-602. doi: 10.1073/pnas.1003026107. Epub 2010 Aug 2. Proc Natl Acad Sci U S A. 2010. PMID: 20679249 Free PMC article.