Uenaka T - Search Results

1

E7080, a novel inhibitor that targets multiple kinases, has potent antitumor activities against stem cell factor producing human small cell lung cancer H146, based on angiogenesis inhibition.

Matsui J, Yamamoto Y, Funahashi Y, Tsuruoka A, Watanabe T, Wakabayashi T, Uenaka T, Asada M. Matsui J, et al. Among authors: uenaka t. Int J Cancer. 2008 Feb 1;122(3):664-71. doi: 10.1002/ijc.23131. Int J Cancer. 2008. PMID: 17943726

2

Antitumor activity of ER-37328, a novel carbazole topoisomerase II inhibitor.

Nakamura K, Sugumi H, Yamaguchi A, Uenaka T, Kotake Y, Okada T, Kamata J, Niijima J, Nagasu T, Koyanagi N, Yoshino H, Kitoh K, Yoshimatsu K. Nakamura K, et al. Among authors: uenaka t. Mol Cancer Ther. 2002 Jan;1(3):169-75. Mol Cancer Ther. 2002. PMID: 12467211

3

A novel carbazole topoisomerase II poison, ER-37328: potent tumoricidal activity against human solid tumors in vitro and in vivo.

Nakamura K, Uenaka T, Nagasu T, Sugumi H, Yamaguchi A, Kotake Y, Okada T, Kamata J, Niijima J, Taniguchi T, Koyanagi N, Yoshino H, Kitoh K, Yoshimatsu K. Nakamura K, et al. Among authors: uenaka t. Cancer Sci. 2003 Jan;94(1):119-24. doi: 10.1111/j.1349-7006.2003.tb01362.x. Cancer Sci. 2003. PMID: 12708485 Free PMC article.

4

Pladienolides, new substances from culture of Streptomyces platensis Mer-11107. III. In vitro and in vivo antitumor activities.

Mizui Y, Sakai T, Iwata M, Uenaka T, Okamoto K, Shimizu H, Yamori T, Yoshimatsu K, Asada M. Mizui Y, et al. Among authors: uenaka t. J Antibiot (Tokyo). 2004 Mar;57(3):188-96. doi: 10.7164/antibiotics.57.188. J Antibiot (Tokyo). 2004. PMID: 15152804 Free article.

5

Multi-kinase inhibitor E7080 suppresses lymph node and lung metastases of human mammary breast tumor MDA-MB-231 via inhibition of vascular endothelial growth factor-receptor (VEGF-R) 2 and VEGF-R3 kinase.

Matsui J, Funahashi Y, Uenaka T, Watanabe T, Tsuruoka A, Asada M. Matsui J, et al. Among authors: uenaka t. Clin Cancer Res. 2008 Sep 1;14(17):5459-65. doi: 10.1158/1078-0432.CCR-07-5270. Clin Cancer Res. 2008. PMID: 18765537

6

E7080, a multi-tyrosine kinase inhibitor, suppresses the progression of malignant pleural mesothelioma with different proangiogenic cytokine production profiles.

Ikuta K, Yano S, Trung VT, Hanibuchi M, Goto H, Li Q, Wang W, Yamada T, Ogino H, Kakiuchi S, Uehara H, Sekido Y, Uenaka T, Nishioka Y, Sone S. Ikuta K, et al. Among authors: uenaka t. Clin Cancer Res. 2009 Dec 1;15(23):7229-37. doi: 10.1158/1078-0432.CCR-09-1980. Epub 2009 Nov 24. Clin Cancer Res. 2009. PMID: 19934291

7

Antitumour activity of oral E7080, a novel inhibitor of multiple tyrosine kinases, in human sarcoma xenografts.

Bruheim S, Kristian A, Uenaka T, Suo Z, Tsuruoka A, Nesland JM, Fodstad Ø. Bruheim S, et al. Among authors: uenaka t. Int J Cancer. 2011 Aug 1;129(3):742-50. doi: 10.1002/ijc.25922. Epub 2011 Mar 25. Int J Cancer. 2011. PMID: 21225632

8

E7080 suppresses hematogenous multiple organ metastases of lung cancer cells with nonmutated epidermal growth factor receptor.

Ogino H, Hanibuchi M, Kakiuchi S, Trung VT, Goto H, Ikuta K, Yamada T, Uehara H, Tsuruoka A, Uenaka T, Wang W, Li Q, Takeuchi S, Yano S, Nishioka Y, Sone S. Ogino H, et al. Among authors: uenaka t. Mol Cancer Ther. 2011 Jul;10(7):1218-28. doi: 10.1158/1535-7163.MCT-10-0707. Epub 2011 May 6. Mol Cancer Ther. 2011. PMID: 21551260

9

Selective inhibition of EZH2 by EPZ-6438 leads to potent antitumor activity in EZH2-mutant non-Hodgkin lymphoma.

Knutson SK, Kawano S, Minoshima Y, Warholic NM, Huang KC, Xiao Y, Kadowaki T, Uesugi M, Kuznetsov G, Kumar N, Wigle TJ, Klaus CR, Allain CJ, Raimondi A, Waters NJ, Smith JJ, Porter-Scott M, Chesworth R, Moyer MP, Copeland RA, Richon VM, Uenaka T, Pollock RM, Kuntz KW, Yokoi A, Keilhack H. Knutson SK, et al. Among authors: uenaka t. Mol Cancer Ther. 2014 Apr;13(4):842-54. doi: 10.1158/1535-7163.MCT-13-0773. Epub 2014 Feb 21. Mol Cancer Ther. 2014. PMID: 24563539

10

Enhanced anti-angiogenic effect of E7820 in combination with erlotinib in epidermal growth factor receptor-tyrosine kinase inhibitor-resistant non-small-cell lung cancer xenograft models.

Ito K, Semba T, Uenaka T, Wakabayashi T, Asada M, Funahashi Y. Ito K, et al. Among authors: uenaka t. Cancer Sci. 2014 Aug;105(8):1023-31. doi: 10.1111/cas.12450. Cancer Sci. 2014. PMID: 24841832 Free PMC article.

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