Stefan E - Search Results

1

Quantification of dynamic protein complexes using Renilla luciferase fragment complementation applied to protein kinase A activities in vivo.

Stefan E, Aquin S, Berger N, Landry CR, Nyfeler B, Bouvier M, Michnick SW. Stefan E, et al. Proc Natl Acad Sci U S A. 2007 Oct 23;104(43):16916-21. doi: 10.1073/pnas.0704257104. Epub 2007 Oct 17. Proc Natl Acad Sci U S A. 2007. PMID: 17942691 Free PMC article.

2

GPR161 structure uncovers the redundant role of sterol-regulated ciliary cAMP signaling in the Hedgehog pathway.

Hoppe N, Harrison S, Hwang SH, Chen Z, Karelina M, Deshpande I, Suomivuori CM, Palicharla VR, Berry SP, Tschaikner P, Regele D, Covey DF, Stefan E, Marks DS, Reiter JF, Dror RO, Evers AS, Mukhopadhyay S, Manglik A. Hoppe N, et al. Among authors: stefan e. Nat Struct Mol Biol. 2024 Apr;31(4):667-677. doi: 10.1038/s41594-024-01223-8. Epub 2024 Feb 7. Nat Struct Mol Biol. 2024. PMID: 38326651 Free PMC article.

3

Missense variant interaction scanning reveals a critical role of the FERM domain for tumor suppressor protein NF2 conformation and function.

Moesslacher CS, Auernig E, Woodsmith J, Feichtner A, Jany-Luig E, Jehle S, Worseck JM, Heine CL, Stefan E, Stelzl U. Moesslacher CS, et al. Among authors: stefan e. Life Sci Alliance. 2023 Jun 6;6(8):e202302043. doi: 10.26508/lsa.202302043. Print 2023 Aug. Life Sci Alliance. 2023. PMID: 37280085 Free PMC article.

4

Disruptor: Computational identification of oncogenic mutants disrupting protein-protein and protein-DNA interactions.

Kugler V, Lieb A, Guerin N, Donald BR, Stefan E, Kaserer T. Kugler V, et al. Among authors: stefan e. Commun Biol. 2023 Jul 13;6(1):720. doi: 10.1038/s42003-023-05089-2. Commun Biol. 2023. PMID: 37443295 Free PMC article.

5

Kinase perturbations redirect mitochondrial function in cancer.

Torres-Quesada O, Strich S, Stefan E. Torres-Quesada O, et al. Among authors: stefan e. Bioenerg Commun. 2022 Nov 15;2022:17. doi: 10.26124/bec:2022-0013. Bioenerg Commun. 2022. PMID: 37081928 Free PMC article.

6

Tracking and blocking interdependencies of cellular BRAF-MEK oncokinase activities.

Fleischmann J, Schwaighofer S, De Falco L, Enzler F, Feichtner A, Kugler V, Tschaikner P, Huber RG, Stefan E. Fleischmann J, et al. Among authors: stefan e. PNAS Nexus. 2023 Jun 5;2(6):pgad185. doi: 10.1093/pnasnexus/pgad185. eCollection 2023 Jun. PNAS Nexus. 2023. PMID: 37325027 Free PMC article.

7

Universal strategies in research and drug discovery based on protein-fragment complementation assays.

Michnick SW, Ear PH, Manderson EN, Remy I, Stefan E. Michnick SW, et al. Among authors: stefan e. Nat Rev Drug Discov. 2007 Jul;6(7):569-82. doi: 10.1038/nrd2311. Nat Rev Drug Discov. 2007. PMID: 17599086 Review.

8

Identification of ERGIC-53 as an intracellular transport receptor of alpha1-antitrypsin.

Nyfeler B, Reiterer V, Wendeler MW, Stefan E, Zhang B, Michnick SW, Hauri HP. Nyfeler B, et al. Among authors: stefan e. J Cell Biol. 2008 Feb 25;180(4):705-12. doi: 10.1083/jcb.200709100. Epub 2008 Feb 18. J Cell Biol. 2008. PMID: 18283111 Free PMC article.

9

Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitors.

Skoumbourdis AP, Leclair CA, Stefan E, Turjanski AG, Maguire W, Titus SA, Huang R, Auld DS, Inglese J, Austin CP, Michnick SW, Xia M, Thomas CJ. Skoumbourdis AP, et al. Among authors: stefan e. Bioorg Med Chem Lett. 2009 Jul 1;19(13):3686-92. doi: 10.1016/j.bmcl.2009.01.057. Epub 2009 Jan 23. Bioorg Med Chem Lett. 2009. PMID: 19464886 Free PMC article.

10

PKA regulatory subunits mediate synergy among conserved G-protein-coupled receptor cascades.

Stefan E, Malleshaiah MK, Breton B, Ear PH, Bachmann V, Beyermann M, Bouvier M, Michnick SW. Stefan E, et al. Nat Commun. 2011 Dec 20;2:598. doi: 10.1038/ncomms1605. Nat Commun. 2011. PMID: 22186894 Free PMC article.

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