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Selective incorporation of polyanionic molecules into hamster prions.
Geoghegan JC, Valdes PA, Orem NR, Deleault NR, Williamson RA, Harris BT, Supattapone S. Geoghegan JC, et al. Among authors: supattapone s. J Biol Chem. 2007 Dec 14;282(50):36341-53. doi: 10.1074/jbc.M704447200. Epub 2007 Oct 16. J Biol Chem. 2007. PMID: 17940287 Free PMC article.
We previously showed that the protein misfolding cyclic amplification (PMCA) technique can be used to form infectious prion molecules de novo from purified native PrPC molecules in an autocatalytic process requiring accessory polyanions (Deleault, N. R., Harris, B. T., Rees, J. R …
We previously showed that the protein misfolding cyclic amplification (PMCA) technique can be used to form infectious prion molecules de nov …
Anti-prion drugs do not improve survival in knock-in models of inherited prion disease.
Walsh DJ, Rees JR, Mehra S, Bourkas MEC, Kaczmarczyk L, Stuart E, Jackson WS, Watts JC, Supattapone S. Walsh DJ, et al. Among authors: supattapone s. bioRxiv [Preprint]. 2023 Sep 29:2023.09.28.559951. doi: 10.1101/2023.09.28.559951. bioRxiv. 2023. Update in: PLoS Pathog. 2024 Apr 1;20(4):e1012087. doi: 10.1371/journal.ppat.1012087 PMID: 37808761 Free PMC article. Updated. Preprint.
RNA molecules stimulate prion protein conversion.
Deleault NR, Lucassen RW, Supattapone S. Deleault NR, et al. Among authors: supattapone s. Nature. 2003 Oct 16;425(6959):717-20. doi: 10.1038/nature01979. Nature. 2003. PMID: 14562104
Prion protein conversion in vitro.
Supattapone S. Supattapone S. J Mol Med (Berl). 2004 Jun;82(6):348-56. doi: 10.1007/s00109-004-0534-3. Epub 2004 Mar 10. J Mol Med (Berl). 2004. PMID: 15014886 Review.
Copper (II) ions potently inhibit purified PrPres amplification.
Orem NR, Geoghegan JC, Deleault NR, Kascsak R, Supattapone S. Orem NR, et al. Among authors: supattapone s. J Neurochem. 2006 Mar;96(5):1409-15. doi: 10.1111/j.1471-4159.2006.03650.x. Epub 2006 Jan 17. J Neurochem. 2006. PMID: 16417569 Free article.
98 results