Smith CE - Search Results

1

Phenylpiperidine-benzoxazinones as urotensin-II receptor antagonists: synthesis, SAR, and in vivo assessment.

Luci DK, Ghosh S, Smith CE, Qi J, Wang Y, Haertlein B, Parry TJ, Li J, Almond HR Jr, Minor LK, Damiano BP, Kinney WA, Maryanoff BE, Lawson EC. Luci DK, et al. Among authors: smith ce. Bioorg Med Chem Lett. 2007 Dec 1;17(23):6489-92. doi: 10.1016/j.bmcl.2007.09.092. Epub 2007 Oct 1. Bioorg Med Chem Lett. 2007. PMID: 17933531

2

Characterization of functional urotensin II receptors in human skeletal muscle myoblasts: comparison with angiotensin II receptors.

Qi JS, Minor LK, Smith C, Hu B, Yang J, Andrade-Gordon P, Damiano B. Qi JS, et al. Peptides. 2005 Apr;26(4):683-90. doi: 10.1016/j.peptides.2004.11.018. Epub 2005 Jan 1. Peptides. 2005. PMID: 15752584

3

Novel indolylindazolylmaleimides as inhibitors of protein kinase C-beta: synthesis, biological activity, and cardiovascular safety.

Zhang HC, Derian CK, McComsey DF, White KB, Ye H, Hecker LR, Li J, Addo MF, Croll D, Eckardt AJ, Smith CE, Li Q, Cheung WM, Conway BR, Emanuel S, Demarest KT, Andrade-Gordon P, Damiano BP, Maryanoff BE. Zhang HC, et al. Among authors: smith ce. J Med Chem. 2005 Mar 24;48(6):1725-8. doi: 10.1021/jm049478u. J Med Chem. 2005. PMID: 15771419

4

Nonpeptide urotensin-II receptor antagonists: a new ligand class based on piperazino-phthalimide and piperazino-isoindolinone subunits.

Lawson EC, Luci DK, Ghosh S, Kinney WA, Reynolds CH, Qi J, Smith CE, Wang Y, Minor LK, Haertlein BJ, Parry TJ, Damiano BP, Maryanoff BE. Lawson EC, et al. Among authors: smith ce. J Med Chem. 2009 Dec 10;52(23):7432-45. doi: 10.1021/jm900683d. J Med Chem. 2009. PMID: 19731961

5

A thiocarbamate inhibitor of endothelial lipase raises HDL cholesterol levels in mice.

Greco MN, Connelly MA, Leo GC, Olson MW, Powell E, Huang Z, Hawkins M, Smith C, Schalk-Hihi C, Darrow AL, Xin H, Lang W, Damiano BP, Hlasta DJ. Greco MN, et al. Bioorg Med Chem Lett. 2013 May 1;23(9):2595-7. doi: 10.1016/j.bmcl.2013.02.113. Epub 2013 Mar 7. Bioorg Med Chem Lett. 2013. PMID: 23528297

6

Structure-function analysis of urotensin II and its use in the construction of a ligand-receptor working model.

Kinney WA, Almond HR Jr, Qi J, Smith CE, Santulli RJ, de Garavilla L, Andrade-Gordon P, Cho DS, Everson AM, Feinstein MA, Leung PA, Maryanoff BE. Kinney WA, et al. Among authors: smith ce. Angew Chem Int Ed Engl. 2002 Aug 16;41(16):2940-4. doi: 10.1002/1521-3773(20020816)41:16<2940::AID-ANIE2940>3.0.CO;2-M. Angew Chem Int Ed Engl. 2002. PMID: 12203418 No abstract available.

7

Design, synthesis, and biological characterization of a peptide-mimetic antagonist for a tethered-ligand receptor.

Andrade-Gordon P, Maryanoff BE, Derian CK, Zhang HC, Addo MF, Darrow AL, Eckardt AJ, Hoekstra WJ, McComsey DF, Oksenberg D, Reynolds EE, Santulli RJ, Scarborough RM, Smith CE, White KB. Andrade-Gordon P, et al. Among authors: smith ce. Proc Natl Acad Sci U S A. 1999 Oct 26;96(22):12257-62. doi: 10.1073/pnas.96.22.12257. Proc Natl Acad Sci U S A. 1999. PMID: 10535908 Free PMC article.

8

High-content assays for evaluating cellular and hepatic diacylglycerol acyltransferase activity.

Qi J, Lang W, Giardino E, Caldwell GW, Smith C, Minor LK, Darrow AL, Willemsens G, Dewaepenaert K, Roevens P, Linders JT, Liang Y, Connelly MA. Qi J, et al. J Lipid Res. 2010 Dec;51(12):3559-67. doi: 10.1194/jlr.D008029. Epub 2010 Aug 28. J Lipid Res. 2010. PMID: 20805092 Free PMC article.

9

Protease-activated receptor-2 (PAR-2): structure-function study of receptor activation by diverse peptides related to tethered-ligand epitopes.

Maryanoff BE, Santulli RJ, McComsey DF, Hoekstra WJ, Hoey K, Smith CE, Addo M, Darrow AL, Andrade-Gordon P. Maryanoff BE, et al. Among authors: smith ce. Arch Biochem Biophys. 2001 Feb 15;386(2):195-204. doi: 10.1006/abbi.2000.2207. Arch Biochem Biophys. 2001. PMID: 11368342

10

A novel fluorogenic substrate for the measurement of endothelial lipase activity.

Darrow AL, Olson MW, Xin H, Burke SL, Smith C, Schalk-Hihi C, Williams R, Bayoumy SS, Deckman IC, Todd MJ, Damiano BP, Connelly MA. Darrow AL, et al. J Lipid Res. 2011 Feb;52(2):374-82. doi: 10.1194/jlr.D007971. J Lipid Res. 2011. PMID: 21062953 Free PMC article.

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