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Vascular adhesion protein-1 promotes liver inflammation and drives hepatic fibrosis.
Weston CJ, Shepherd EL, Claridge LC, Rantakari P, Curbishley SM, Tomlinson JW, Hubscher SG, Reynolds GM, Aalto K, Anstee QM, Jalkanen S, Salmi M, Smith DJ, Day CP, Adams DH. Weston CJ, et al. Among authors: smith dj. J Clin Invest. 2015 Feb;125(2):501-20. doi: 10.1172/JCI73722. Epub 2014 Dec 22. J Clin Invest. 2015. PMID: 25562318 Free PMC article. Clinical Trial.
Vascular adhesion protein-1 is elevated in primary sclerosing cholangitis, is predictive of clinical outcome and facilitates recruitment of gut-tropic lymphocytes to liver in a substrate-dependent manner.
Trivedi PJ, Tickle J, Vesterhus MN, Eddowes PJ, Bruns T, Vainio J, Parker R, Smith D, Liaskou E, Thorbjørnsen LW, Hirschfield GM, Auvinen K, Hubscher SG, Salmi M, Adams DH, Weston CJ. Trivedi PJ, et al. Gut. 2018 Jun;67(6):1135-1145. doi: 10.1136/gutjnl-2016-312354. Epub 2017 Apr 20. Gut. 2018. PMID: 28428344 Free PMC article.
Vascular adhesion protein-1 blockade in primary sclerosing cholangitis: Open-label, multicenter, single-arm, phase II trial.
Hirschfield GM, Arndtz K, Kirkham A, Chen YY, Fox R, Rowe A, Douglas-Pugh J, Thorburn D, Barnes E, Aithal GP, Hull D, Bhandal K, Olsen K, Woodward P, Lax S, Newsome P, Smith DJ, Kallio A, Adams DH, Homer V, Weston CJ. Hirschfield GM, et al. Among authors: smith dj. Hepatol Commun. 2024 Apr 26;8(5):e0426. doi: 10.1097/HC9.0000000000000426. eCollection 2024 May 1. Hepatol Commun. 2024. PMID: 38668724 Free article. Clinical Trial.
Vascular adhesion protein-1 in human ischaemic stroke.
Airas L, Lindsberg PJ, Karjalainen-Lindsberg ML, Mononen I, Kotisaari K, Smith DJ, Jalkanen S. Airas L, et al. Among authors: smith dj. Neuropathol Appl Neurobiol. 2008 Aug;34(4):394-402. doi: 10.1111/j.1365-2990.2007.00911.x. Epub 2007 Nov 14. Neuropathol Appl Neurobiol. 2008. PMID: 18005095
1,807 results