Plun-Favreau H - Search Results

1

The mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1.

Plun-Favreau H, Klupsch K, Moisoi N, Gandhi S, Kjaer S, Frith D, Harvey K, Deas E, Harvey RJ, McDonald N, Wood NW, Martins LM, Downward J. Plun-Favreau H, et al. Nat Cell Biol. 2007 Nov;9(11):1243-52. doi: 10.1038/ncb1644. Epub 2007 Sep 30. Nat Cell Biol. 2007. PMID: 17906618

2

The non-specific lethal complex regulates genes and pathways genetically linked to Parkinson's disease.

Hicks AR, Reynolds RH, O'Callaghan B, García-Ruiz S, Gil-Martínez AL, Botía J, Plun-Favreau H, Ryten M. Hicks AR, et al. Among authors: plun favreau h. Brain. 2023 Dec 1;146(12):4974-4987. doi: 10.1093/brain/awad246. Brain. 2023. PMID: 37522749 Free PMC article.

3

Loss of function mutations in the gene encoding Omi/HtrA2 in Parkinson's disease.

Strauss KM, Martins LM, Plun-Favreau H, Marx FP, Kautzmann S, Berg D, Gasser T, Wszolek Z, Müller T, Bornemann A, Wolburg H, Downward J, Riess O, Schulz JB, Krüger R. Strauss KM, et al. Hum Mol Genet. 2005 Aug 1;14(15):2099-111. doi: 10.1093/hmg/ddi215. Epub 2005 Jun 16. Hum Mol Genet. 2005. PMID: 15961413

4

Emerging pathways in genetic Parkinson's disease: autosomal-recessive genes in Parkinson's disease--a common pathway?

Fitzgerald JC, Plun-Favreau H. Fitzgerald JC, et al. FEBS J. 2008 Dec;275(23):5758-66. doi: 10.1111/j.1742-4658.2008.06708.x. FEBS J. 2008. PMID: 19021753 Free article. Review.

5

Mitochondrial dysfunction triggered by loss of HtrA2 results in the activation of a brain-specific transcriptional stress response.

Moisoi N, Klupsch K, Fedele V, East P, Sharma S, Renton A, Plun-Favreau H, Edwards RE, Teismann P, Esposti MD, Morrison AD, Wood NW, Downward J, Martins LM. Moisoi N, et al. Cell Death Differ. 2009 Mar;16(3):449-64. doi: 10.1038/cdd.2008.166. Epub 2008 Nov 21. Cell Death Differ. 2009. PMID: 19023330

6

What have PINK1 and HtrA2 genes told us about the role of mitochondria in Parkinson's disease?

Plun-Favreau H, Gandhi S, Wood-Kaczmar A, Deas E, Yao Z, Wood NW. Plun-Favreau H, et al. Ann N Y Acad Sci. 2008 Dec;1147:30-6. doi: 10.1196/annals.1427.032. Ann N Y Acad Sci. 2008. PMID: 19076428

7

Drosophila HtrA2 is dispensable for apoptosis but acts downstream of PINK1 independently from Parkin.

Tain LS, Chowdhury RB, Tao RN, Plun-Favreau H, Moisoi N, Martins LM, Downward J, Whitworth AJ, Tapon N. Tain LS, et al. Cell Death Differ. 2009 Aug;16(8):1118-25. doi: 10.1038/cdd.2009.23. Epub 2009 Mar 13. Cell Death Differ. 2009. PMID: 19282869 Free PMC article.

8

PINK1-associated Parkinson's disease is caused by neuronal vulnerability to calcium-induced cell death.

Gandhi S, Wood-Kaczmar A, Yao Z, Plun-Favreau H, Deas E, Klupsch K, Downward J, Latchman DS, Tabrizi SJ, Wood NW, Duchen MR, Abramov AY. Gandhi S, et al. Mol Cell. 2009 Mar 13;33(5):627-38. doi: 10.1016/j.molcel.2009.02.013. Mol Cell. 2009. PMID: 19285945 Free PMC article.

9

PINK1 function in health and disease.

Deas E, Plun-Favreau H, Wood NW. Deas E, et al. EMBO Mol Med. 2009 Jun;1(3):152-65. doi: 10.1002/emmm.200900024. EMBO Mol Med. 2009. PMID: 20049715 Free PMC article. Review.

10

Targeting mitochondrial dysfunction in neurodegenerative disease: Part I.

Burchell VS, Gandhi S, Deas E, Wood NW, Abramov AY, Plun-Favreau H. Burchell VS, et al. Expert Opin Ther Targets. 2010 Apr;14(4):369-85. doi: 10.1517/14728221003652489. Expert Opin Ther Targets. 2010. PMID: 20184395 Review.

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