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Evaluation of the ELOVL4 gene in patients with age-related macular degeneration.
Ayyagari R, Zhang K, Hutchinson A, Yu Z, Swaroop A, Kakuk LE, Seddon JM, Bernstein PS, Lewis RA, Tammur J, Yang Z, Li Y, Zhang H, Yashar BM, Liu J, Petrukhin K, Sieving PA, Allikmets R. Ayyagari R, et al. Among authors: zhang k, zhang h. Ophthalmic Genet. 2001 Dec;22(4):233-9. doi: 10.1076/opge.22.4.233.2219. Ophthalmic Genet. 2001. PMID: 11803489
Lipofuscin accumulation, abnormal electrophysiology, and photoreceptor degeneration in mutant ELOVL4 transgenic mice: a model for macular degeneration.
Karan G, Lillo C, Yang Z, Cameron DJ, Locke KG, Zhao Y, Thirumalaichary S, Li C, Birch DG, Vollmer-Snarr HR, Williams DS, Zhang K. Karan G, et al. Among authors: zhang k. Proc Natl Acad Sci U S A. 2005 Mar 15;102(11):4164-9. doi: 10.1073/pnas.0407698102. Epub 2005 Mar 4. Proc Natl Acad Sci U S A. 2005. PMID: 15749821 Free PMC article.
CFH Y402H confers similar risk of soft drusen and both forms of advanced AMD.
Magnusson KP, Duan S, Sigurdsson H, Petursson H, Yang Z, Zhao Y, Bernstein PS, Ge J, Jonasson F, Stefansson E, Helgadottir G, Zabriskie NA, Jonsson T, Björnsson A, Thorlacius T, Jonsson PV, Thorleifsson G, Kong A, Stefansson H, Zhang K, Stefansson K, Gulcher JR. Magnusson KP, et al. Among authors: zhang k. PLoS Med. 2006 Jan;3(1):e5. doi: 10.1371/journal.pmed.0030005. Epub 2005 Nov 29. PLoS Med. 2006. PMID: 16300415 Free PMC article.
A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration.
Yang Z, Camp NJ, Sun H, Tong Z, Gibbs D, Cameron DJ, Chen H, Zhao Y, Pearson E, Li X, Chien J, Dewan A, Harmon J, Bernstein PS, Shridhar V, Zabriskie NA, Hoh J, Howes K, Zhang K. Yang Z, et al. Among authors: zhang k. Science. 2006 Nov 10;314(5801):992-3. doi: 10.1126/science.1133811. Epub 2006 Oct 19. Science. 2006. PMID: 17053109
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