Hutcheson IR - Search Results

1

Insulin receptor substrate-1 involvement in epidermal growth factor receptor and insulin-like growth factor receptor signalling: implication for Gefitinib ('Iressa') response and resistance.

Knowlden JM, Jones HE, Barrow D, Gee JM, Nicholson RI, Hutcheson IR. Knowlden JM, et al. Among authors: hutcheson ir. Breast Cancer Res Treat. 2008 Sep;111(1):79-91. doi: 10.1007/s10549-007-9763-9. Epub 2007 Sep 28. Breast Cancer Res Treat. 2008. PMID: 17902048

2

The biology of antihormone failure in breast cancer.

Nicholson RI, Gee JM, Knowlden J, McClelland R, Madden TA, Barrow D, Hutcheson I. Nicholson RI, et al. Breast Cancer Res Treat. 2003;80 Suppl 1:S29-34; discussion S35. doi: 10.1023/a:1025467500433. Breast Cancer Res Treat. 2003. PMID: 14535532 Review.

3

Elevated levels of epidermal growth factor receptor/c-erbB2 heterodimers mediate an autocrine growth regulatory pathway in tamoxifen-resistant MCF-7 cells.

Knowlden JM, Hutcheson IR, Jones HE, Madden T, Gee JM, Harper ME, Barrow D, Wakeling AE, Nicholson RI. Knowlden JM, et al. Among authors: hutcheson ir. Endocrinology. 2003 Mar;144(3):1032-44. doi: 10.1210/en.2002-220620. Endocrinology. 2003. PMID: 12586780

4

Oestrogen receptor-mediated modulation of the EGFR/MAPK pathway in tamoxifen-resistant MCF-7 cells.

Hutcheson IR, Knowlden JM, Madden TA, Barrow D, Gee JM, Wakeling AE, Nicholson RI. Hutcheson IR, et al. Breast Cancer Res Treat. 2003 Sep;81(1):81-93. doi: 10.1023/A:1025484908380. Breast Cancer Res Treat. 2003. PMID: 14531500

5

Nonendocrine pathways and endocrine resistance: observations with antiestrogens and signal transduction inhibitors in combination.

Nicholson RI, Hutcheson IR, Knowlden JM, Jones HE, Harper ME, Jordan N, Hiscox SE, Barrow D, Gee JM. Nicholson RI, et al. Among authors: hutcheson ir. Clin Cancer Res. 2004 Jan 1;10(1 Pt 2):346S-54S. doi: 10.1158/1078-0432.ccr-031206. Clin Cancer Res. 2004. PMID: 14734490

6

Understanding endocrine resistance: the critical need for sequential samples from clinical breast cancer and novel in vitro models.

Gee JM, Hutcheson IR. Gee JM, et al. Among authors: hutcheson ir. Breast Cancer Res. 2005;7(5):187-9. doi: 10.1186/bcr1289. Epub 2005 Jul 18. Breast Cancer Res. 2005. PMID: 16168136 Free PMC article. No abstract available.

7

Growth factor receptor interplay and resistance in cancer.

Jones HE, Gee JM, Hutcheson IR, Knowlden JM, Barrow D, Nicholson RI. Jones HE, et al. Among authors: hutcheson ir. Endocr Relat Cancer. 2006 Dec;13 Suppl 1:S45-51. doi: 10.1677/erc.1.01275. Endocr Relat Cancer. 2006. PMID: 17259558 Review.

8

Inductive mechanisms limiting response to anti-epidermal growth factor receptor therapy.

Hutcheson IR, Knowlden JM, Jones HE, Burmi RS, McClelland RA, Barrow D, Gee JM, Nicholson RI. Hutcheson IR, et al. Endocr Relat Cancer. 2006 Dec;13 Suppl 1:S89-97. doi: 10.1677/erc.1.01279. Endocr Relat Cancer. 2006. PMID: 17259562 Review.

9

Heregulin beta1 drives gefitinib-resistant growth and invasion in tamoxifen-resistant MCF-7 breast cancer cells.

Hutcheson IR, Knowlden JM, Hiscox SE, Barrow D, Gee JM, Robertson JF, Ellis IO, Nicholson RI. Hutcheson IR, et al. Breast Cancer Res. 2007;9(4):R50. doi: 10.1186/bcr1754. Breast Cancer Res. 2007. PMID: 17686159 Free PMC article.

10

Growth of hormone-dependent MCF-7 breast cancer cells is promoted by constitutive caveolin-1 whose expression is lost in an EGF-R-mediated manner during development of tamoxifen resistance.

Thomas NB, Hutcheson IR, Campbell L, Gee J, Taylor KM, Nicholson RI, Gumbleton M. Thomas NB, et al. Among authors: hutcheson ir. Breast Cancer Res Treat. 2010 Feb;119(3):575-91. doi: 10.1007/s10549-009-0355-8. Epub 2009 Mar 15. Breast Cancer Res Treat. 2010. PMID: 19288272

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