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Angiogenesis inhibitor DC101 delays growth of intracerebral glioblastoma but induces morbidity when combined with irradiation.
Verhoeff JJ, Stalpers LJ, Van Noorden CJ, Troost D, Ramkema MD, van Bree C, Song JY, Donker M, Chekenya M, Vandertop WP, Richel DJ, van Furth WR. Verhoeff JJ, et al. Among authors: van bree c, van furth wr, van noorden cj. Cancer Lett. 2009 Nov 18;285(1):39-45. doi: 10.1016/j.canlet.2009.04.038. Epub 2009 May 26. Cancer Lett. 2009. PMID: 19473756
The combination of IDH1 mutations and MGMT methylation status predicts survival in glioblastoma better than either IDH1 or MGMT alone.
Molenaar RJ, Verbaan D, Lamba S, Zanon C, Jeuken JW, Boots-Sprenger SH, Wesseling P, Hulsebos TJ, Troost D, van Tilborg AA, Leenstra S, Vandertop WP, Bardelli A, van Noorden CJ, Bleeker FE. Molenaar RJ, et al. Among authors: van tilborg aa, van noorden cj. Neuro Oncol. 2014 Sep;16(9):1263-73. doi: 10.1093/neuonc/nou005. Epub 2014 Feb 6. Neuro Oncol. 2014. PMID: 24510240 Free PMC article.
Mutational profiling of kinases in glioblastoma.
Bleeker FE, Lamba S, Zanon C, Molenaar RJ, Hulsebos TJ, Troost D, van Tilborg AA, Vandertop WP, Leenstra S, van Noorden CJ, Bardelli A. Bleeker FE, et al. Among authors: van tilborg aa, van noorden cj. BMC Cancer. 2014 Sep 26;14:718. doi: 10.1186/1471-2407-14-718. BMC Cancer. 2014. PMID: 25256166 Free PMC article.
Radioprotection of IDH1-Mutated Cancer Cells by the IDH1-Mutant Inhibitor AGI-5198.
Molenaar RJ, Botman D, Smits MA, Hira VV, van Lith SA, Stap J, Henneman P, Khurshed M, Lenting K, Mul AN, Dimitrakopoulou D, van Drunen CM, Hoebe RA, Radivoyevitch T, Wilmink JW, Maciejewski JP, Vandertop WP, Leenders WP, Bleeker FE, van Noorden CJ. Molenaar RJ, et al. Among authors: van drunen cm, van lith sa, van noorden cj. Cancer Res. 2015 Nov 15;75(22):4790-802. doi: 10.1158/0008-5472.CAN-14-3603. Epub 2015 Sep 11. Cancer Res. 2015. PMID: 26363012
381 results