Bremner JB - Search Results

1

An investigation into the cytotoxicity and mode of action of some novel N-alkyl-substituted isatins.

Vine KL, Locke JM, Ranson M, Pyne SG, Bremner JB. Vine KL, et al. Among authors: bremner jb. J Med Chem. 2007 Oct 18;50(21):5109-17. doi: 10.1021/jm0704189. Epub 2007 Sep 21. J Med Chem. 2007. PMID: 17887662

2

Ligand design for alpha(1) adrenoceptors.

Bremner JB, Griffith R, Coban B. Bremner JB, et al. Curr Med Chem. 2001 May;8(6):607-20. doi: 10.2174/0929867013373110. Curr Med Chem. 2001. PMID: 11281844 Review.

3

Synthesis and nicotinic receptor activity of a hydroxylated tropane.

Bremner JB, Godfrey CA, Jensen AA, Smith RJ. Bremner JB, et al. Bioorg Med Chem Lett. 2004 Jan 5;14(1):271-3. doi: 10.1016/j.bmcl.2003.09.081. Bioorg Med Chem Lett. 2004. PMID: 14684341

4

Synthesis and biological evaluation of bicyclic and tricyclic substituted nortropane derivatives: discovery of a novel selective alpha1D-adrenergic receptor ligand.

McGinty SJ, Finch A, Griffith R, Graham RM, Bremner JB. McGinty SJ, et al. Among authors: bremner jb. Bioorg Med Chem. 2004 Nov 1;12(21):5639-50. doi: 10.1016/j.bmc.2004.07.063. Bioorg Med Chem. 2004. PMID: 15465342

5

Synthesis of functionalized 2-aryl-5-nitro-1H-indoles and their activity as bacterial NorA efflux pump inhibitors.

Samosorn S, Bremner JB, Ball A, Lewis K. Samosorn S, et al. Among authors: bremner jb. Bioorg Med Chem. 2006 Feb 1;14(3):857-65. doi: 10.1016/j.bmc.2005.09.019. Epub 2005 Oct 3. Bioorg Med Chem. 2006. PMID: 16203150

6

In vitro cytotoxicity evaluation of some substituted isatin derivatives.

Vine KL, Locke JM, Ranson M, Benkendorff K, Pyne SG, Bremner JB. Vine KL, et al. Among authors: bremner jb. Bioorg Med Chem. 2007 Jan 15;15(2):931-8. doi: 10.1016/j.bmc.2006.10.035. Epub 2006 Oct 20. Bioorg Med Chem. 2007. PMID: 17088067

7

Dual action-based approaches to antibacterial agents.

Bremner JB, Ambrus JI, Samosorn S. Bremner JB, et al. Curr Med Chem. 2007;14(13):1459-77. doi: 10.2174/092986707780831168. Curr Med Chem. 2007. PMID: 17584056 Review.

8

N-phenethyl and N-naphthylmethyl isatins and analogues as in vitro cytotoxic agents.

Matesic L, Locke JM, Bremner JB, Pyne SG, Skropeta D, Ranson M, Vine KL. Matesic L, et al. Among authors: bremner jb. Bioorg Med Chem. 2008 Mar 15;16(6):3118-24. doi: 10.1016/j.bmc.2007.12.026. Epub 2008 Jan 7. Bioorg Med Chem. 2008. PMID: 18182300

9

Structure-activity relationships of 2-aryl-1H-indole inhibitors of the NorA efflux pump in Staphylococcus aureus.

Ambrus JI, Kelso MJ, Bremner JB, Ball AR, Casadei G, Lewis K. Ambrus JI, et al. Among authors: bremner jb. Bioorg Med Chem Lett. 2008 Aug 1;18(15):4294-7. doi: 10.1016/j.bmcl.2008.06.093. Epub 2008 Jul 2. Bioorg Med Chem Lett. 2008. PMID: 18632270 Free PMC article.

10

Synthesis of novel N-protected hydrophobic phenylalanines and their application in potential antibacterials.

Boyle TP, Bremner JB, Coates JA, Deadman J, Keller PA, Pyne SG, Somphol K. Boyle TP, et al. Among authors: bremner jb. Eur J Med Chem. 2009 Mar;44(3):1001-9. doi: 10.1016/j.ejmech.2008.07.001. Epub 2008 Jul 9. Eur J Med Chem. 2009. PMID: 18703256

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