Eiki J - Search Results

1

Metabolic impact of overexpression of liver glycogen synthase with serine-to-alanine substitutions in rat primary hepatocytes.

Kadotani A, Fujimura M, Nakamura T, Ohyama S, Harada N, Maruki H, Tamai Y, Kanatani A, Eiki J, Nagata Y. Kadotani A, et al. Among authors: eiki j. Arch Biochem Biophys. 2007 Oct 15;466(2):283-9. doi: 10.1016/j.abb.2007.08.006. Epub 2007 Aug 22. Arch Biochem Biophys. 2007. PMID: 17880910

2

An allosteric activator of glucokinase impairs the interaction of glucokinase and glucokinase regulatory protein and regulates glucose metabolism.

Futamura M, Hosaka H, Kadotani A, Shimazaki H, Sasaki K, Ohyama S, Nishimura T, Eiki J, Nagata Y. Futamura M, et al. Among authors: eiki j. J Biol Chem. 2006 Dec 8;281(49):37668-74. doi: 10.1074/jbc.M605186200. Epub 2006 Oct 6. J Biol Chem. 2006. PMID: 17028192 Free article.

3

Discovery of novel 2-(pyridine-2-yl)-1H-benzimidazole derivatives as potent glucokinase activators.

Ishikawa M, Nonoshita K, Ogino Y, Nagae Y, Tsukahara D, Hosaka H, Maruki H, Ohyama S, Yoshimoto R, Sasaki K, Nagata Y, Eiki J, Nishimura T. Ishikawa M, et al. Among authors: eiki j. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4450-4. doi: 10.1016/j.bmcl.2009.05.038. Epub 2009 May 18. Bioorg Med Chem Lett. 2009. PMID: 19540111

4

Pharmacokinetic and pharmacodynamic properties of the glucokinase activator MK-0941 in rodent models of type 2 diabetes and healthy dogs.

Eiki J, Nagata Y, Futamura M, Sasaki-Yamamoto K, Iino T, Nishimura T, Chiba M, Ohyama S, Yoshida-Yoshimioto R, Fujii K, Hosaka H, Goto-Shimazaki H, Kadotani A, Ohe T, Lin S, Langdon RB, Berger JP. Eiki J, et al. Mol Pharmacol. 2011 Dec;80(6):1156-65. doi: 10.1124/mol.111.074401. Epub 2011 Sep 21. Mol Pharmacol. 2011. PMID: 21937665

5

Discovery of potent and orally active 3-alkoxy-5-phenoxy-N-thiazolyl benzamides as novel allosteric glucokinase activators.

Iino T, Tsukahara D, Kamata K, Sasaki K, Ohyama S, Hosaka H, Hasegawa T, Chiba M, Nagata Y, Eiki J, Nishimura T. Iino T, et al. Among authors: eiki j. Bioorg Med Chem. 2009 Apr 1;17(7):2733-43. doi: 10.1016/j.bmc.2009.02.038. Epub 2009 Feb 25. Bioorg Med Chem. 2009. PMID: 19282189

6

A selective small molecule glucagon-like peptide-1 secretagogue acting via depolarization-coupled Ca(2+) influx.

Eiki J, Saeki K, Nagano N, Iino T, Yonemoto M, Takayenoki-Iino Y, Ito S, Nishimura T, Sato Y, Bamba M, Watanabe H, Sasaki K, Ohyama S, Kanatani A, Nagase T, Yada T. Eiki J, et al. J Endocrinol. 2009 Jun;201(3):361-7. doi: 10.1677/JOE-08-0528. Epub 2009 Mar 30. J Endocrinol. 2009. PMID: 19332449

7

Discovery and structure-activity relationships of a novel class of quinazoline glucokinase activators.

Iino T, Sasaki Y, Bamba M, Mitsuya M, Ohno A, Kamata K, Hosaka H, Maruki H, Futamura M, Yoshimoto R, Ohyama S, Sasaki K, Chiba M, Ohtake N, Nagata Y, Eiki J, Nishimura T. Iino T, et al. Among authors: eiki j. Bioorg Med Chem Lett. 2009 Oct 1;19(19):5531-8. doi: 10.1016/j.bmcl.2009.08.064. Epub 2009 Aug 21. Bioorg Med Chem Lett. 2009. PMID: 19726182

8

The design and optimization of a series of 2-(pyridin-2-yl)-1H-benzimidazole compounds as allosteric glucokinase activators.

Takahashi K, Hashimoto N, Nakama C, Kamata K, Sasaki K, Yoshimoto R, Ohyama S, Hosaka H, Maruki H, Nagata Y, Eiki J, Nishimura T. Takahashi K, et al. Among authors: eiki j. Bioorg Med Chem. 2009 Oct 1;17(19):7042-51. doi: 10.1016/j.bmc.2009.05.037. Epub 2009 May 21. Bioorg Med Chem. 2009. PMID: 19736020

9

Identification of novel and potent 2-amino benzamide derivatives as allosteric glucokinase activators.

Nishimura T, Iino T, Mitsuya M, Bamba M, Watanabe H, Tsukahara D, Kamata K, Sasaki K, Ohyama S, Hosaka H, Futamura M, Nagata Y, Eiki J. Nishimura T, et al. Among authors: eiki j. Bioorg Med Chem Lett. 2009 Mar 1;19(5):1357-60. doi: 10.1016/j.bmcl.2009.01.053. Epub 2009 Jan 21. Bioorg Med Chem Lett. 2009. PMID: 19188063

10

Discovery of novel 3,6-disubstituted 2-pyridinecarboxamide derivatives as GK activators.

Mitsuya M, Kamata K, Bamba M, Watanabe H, Sasaki Y, Sasaki K, Ohyama S, Hosaka H, Nagata Y, Eiki J, Nishimura T. Mitsuya M, et al. Among authors: eiki j. Bioorg Med Chem Lett. 2009 May 15;19(10):2718-21. doi: 10.1016/j.bmcl.2009.03.137. Epub 2009 Mar 29. Bioorg Med Chem Lett. 2009. PMID: 19362831

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

29 results

Search Page

Filters