Hong JS - Search Results

1

Sinomenine, a natural dextrorotatory morphinan analog, is anti-inflammatory and neuroprotective through inhibition of microglial NADPH oxidase.

Qian L, Xu Z, Zhang W, Wilson B, Hong JS, Flood PM. Qian L, et al. Among authors: hong js. J Neuroinflammation. 2007 Sep 19;4:23. doi: 10.1186/1742-2094-4-23. J Neuroinflammation. 2007. PMID: 17880684 Free PMC article.

2

Role of microglia in inflammation-mediated degeneration of dopaminergic neurons: neuroprotective effect of interleukin 10.

Qian L, Hong JS, Flood PM. Qian L, et al. Among authors: hong js. J Neural Transm Suppl. 2006;(70):367-71. doi: 10.1007/978-3-211-45295-0_56. J Neural Transm Suppl. 2006. PMID: 17017555

3

Interleukin-10 protects lipopolysaccharide-induced neurotoxicity in primary midbrain cultures by inhibiting the function of NADPH oxidase.

Qian L, Block ML, Wei SJ, Lin CF, Reece J, Pang H, Wilson B, Hong JS, Flood PM. Qian L, et al. Among authors: hong js. J Pharmacol Exp Ther. 2006 Oct;319(1):44-52. doi: 10.1124/jpet.106.106351. Epub 2006 Jun 28. J Pharmacol Exp Ther. 2006. PMID: 16807359

4

Microglia-mediated neurotoxicity is inhibited by morphine through an opioid receptor-independent reduction of NADPH oxidase activity.

Qian L, Tan KS, Wei SJ, Wu HM, Xu Z, Wilson B, Lu RB, Hong JS, Flood PM. Qian L, et al. Among authors: hong js. J Immunol. 2007 Jul 15;179(2):1198-209. doi: 10.4049/jimmunol.179.2.1198. J Immunol. 2007. PMID: 17617613

5

NADPH oxidase inhibitor DPI is neuroprotective at femtomolar concentrations through inhibition of microglia over-activation.

Qian L, Gao X, Pei Z, Wu X, Block M, Wilson B, Hong JS, Flood PM. Qian L, et al. Among authors: hong js. Parkinsonism Relat Disord. 2007;13 Suppl 3:S316-20. doi: 10.1016/S1353-8020(08)70023-3. Parkinsonism Relat Disord. 2007. PMID: 18267257

6

Squamosamide derivative FLZ protects dopaminergic neurons against inflammation-mediated neurodegeneration through the inhibition of NADPH oxidase activity.

Zhang D, Hu X, Wei SJ, Liu J, Gao H, Qian L, Wilson B, Liu G, Hong JS. Zhang D, et al. Among authors: hong js. J Neuroinflammation. 2008 May 28;5:21. doi: 10.1186/1742-2094-5-21. J Neuroinflammation. 2008. PMID: 18507839 Free PMC article.

7

Potent anti-inflammatory and neuroprotective effects of TGF-beta1 are mediated through the inhibition of ERK and p47phox-Ser345 phosphorylation and translocation in microglia.

Qian L, Wei SJ, Zhang D, Hu X, Xu Z, Wilson B, El-Benna J, Hong JS, Flood PM. Qian L, et al. Among authors: hong js. J Immunol. 2008 Jul 1;181(1):660-8. doi: 10.4049/jimmunol.181.1.660. J Immunol. 2008. PMID: 18566433 Free PMC article.

8

beta2 Adrenergic receptor activation induces microglial NADPH oxidase activation and dopaminergic neurotoxicity through an ERK-dependent/protein kinase A-independent pathway.

Qian L, Hu X, Zhang D, Snyder A, Wu HM, Li Y, Wilson B, Lu RB, Hong JS, Flood PM. Qian L, et al. Among authors: hong js. Glia. 2009 Nov 15;57(15):1600-9. doi: 10.1002/glia.20873. Glia. 2009. PMID: 19330844 Free PMC article.

9

Neuroinflammation is a key player in Parkinson's disease and a prime target for therapy.

Qian L, Flood PM, Hong JS. Qian L, et al. Among authors: hong js. J Neural Transm (Vienna). 2010 Aug;117(8):971-9. doi: 10.1007/s00702-010-0428-1. Epub 2010 Jun 23. J Neural Transm (Vienna). 2010. PMID: 20571837 Free PMC article. Review.

10

β2-adrenergic receptor activation prevents rodent dopaminergic neurotoxicity by inhibiting microglia via a novel signaling pathway.

Qian L, Wu HM, Chen SH, Zhang D, Ali SF, Peterson L, Wilson B, Lu RB, Hong JS, Flood PM. Qian L, et al. Among authors: hong js. J Immunol. 2011 Apr 1;186(7):4443-54. doi: 10.4049/jimmunol.1002449. Epub 2011 Feb 18. J Immunol. 2011. PMID: 21335487 Free PMC article.

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