Lin L - Search Results

1

Gambogic acid inhibits the catalytic activity of human topoisomerase IIalpha by binding to its ATPase domain.

Qin Y, Meng L, Hu C, Duan W, Zuo Z, Lin L, Zhang X, Ding J. Qin Y, et al. Among authors: lin l. Mol Cancer Ther. 2007 Sep;6(9):2429-40. doi: 10.1158/1535-7163.MCT-07-0147. Mol Cancer Ther. 2007. PMID: 17876042

2

Caspase-8 preferentially senses the apoptosis-inducing action of NG-18, a Gambogic acid derivative, in human leukemia HL-60 cells.

Tao Z, Zhou Y, Lu J, Duan W, Qin Y, He X, Lin L, Ding J. Tao Z, et al. Among authors: lin l. Cancer Biol Ther. 2007 May;6(5):691-6. doi: 10.4161/cbt.6.5.3960. Epub 2007 Feb 3. Cancer Biol Ther. 2007. PMID: 17426447 Free article.

3

A series of alpha-heterocyclic carboxaldehyde thiosemicarbazones inhibit topoisomerase IIalpha catalytic activity.

Huang H, Chen Q, Ku X, Meng L, Lin L, Wang X, Zhu C, Wang Y, Chen Z, Li M, Jiang H, Chen K, Ding J, Liu H. Huang H, et al. Among authors: lin l. J Med Chem. 2010 Apr 22;53(8):3048-64. doi: 10.1021/jm9014394. J Med Chem. 2010. PMID: 20353152

4

Salvicine functions as novel topoisomerase II poison by binding to ATP pocket.

Hu CX, Zuo ZL, Xiong B, Ma JG, Geng MY, Lin LP, Jiang HL, Ding J. Hu CX, et al. Mol Pharmacol. 2006 Nov;70(5):1593-601. doi: 10.1124/mol.106.027714. Epub 2006 Aug 16. Mol Pharmacol. 2006. PMID: 16914642

5

MFTZ-1, an actinomycetes subspecies derived antitumor macrolide, functions as a novel topoisomerase II poison.

Xie CY, Zhu H, Lin LP, Miao ZH, Geng MY, Cai YJ, Chen Y, Zhao HJ, Luo HB, Zhang XW, Fan LM, Shen YM, Ding J. Xie CY, et al. Mol Cancer Ther. 2007 Nov;6(11):3059-70. doi: 10.1158/1535-7163.MCT-07-0014. Mol Cancer Ther. 2007. PMID: 18025289

6

GA3, a new gambogic acid derivative, exhibits potent antitumor activities in vitro via apoptosis-involved mechanisms.

Xie H, Qin YX, Zhou YL, Tong LJ, Lin LP, Geng MY, Duan WH, Ding J. Xie H, et al. Acta Pharmacol Sin. 2009 Mar;30(3):346-54. doi: 10.1038/aps.2009.3. Acta Pharmacol Sin. 2009. PMID: 19262558 Free PMC article.

7

Philinopside A, a novel marine-derived compound possessing dual anti-angiogenic and anti-tumor effects.

Tong Y, Zhang X, Tian F, Yi Y, Xu Q, Li L, Tong L, Lin L, Ding J. Tong Y, et al. Among authors: lin l. Int J Cancer. 2005 May 10;114(6):843-53. doi: 10.1002/ijc.20804. Int J Cancer. 2005. PMID: 15645493

8

PE, a new sulfated saponin from sea cucumber, exhibits anti-angiogenic and anti-tumor activities in vitro and in vivo.

Tian F, Zhang X, Tong Y, Yi Y, Zhang S, Li L, Sun P, Lin L, Ding J. Tian F, et al. Among authors: lin l. Cancer Biol Ther. 2005 Aug;4(8):874-82. doi: 10.4161/cbt.4.8.1917. Cancer Biol Ther. 2005. PMID: 16082187 Free article.

9

Chimmitecan, a novel 9-substituted camptothecin, with improved anticancer pharmacologic profiles in vitro and in vivo.

Huang M, Gao H, Chen Y, Zhu H, Cai Y, Zhang X, Miao Z, Jiang H, Zhang J, Shen H, Lin L, Lu W, Ding J. Huang M, et al. Among authors: lin l. Clin Cancer Res. 2007 Feb 15;13(4):1298-307. doi: 10.1158/1078-0432.CCR-06-1277. Epub 2007 Feb 7. Clin Cancer Res. 2007. PMID: 17287296

10

Reactive oxygen species contribute to cell killing and P-glycoprotein downregulation by salvicine in multidrug resistant K562/A02 cells.

Cai Y, Lu J, Miao Z, Lin L, Ding J. Cai Y, et al. Among authors: lin l. Cancer Biol Ther. 2007 Nov;6(11):1794-9. doi: 10.4161/cbt.6.11.4860. Epub 2007 Aug 12. Cancer Biol Ther. 2007. PMID: 18032928 Free article.

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