Megens AA - Search Results

1

Pharmacokinetic-pharmacodynamic modeling of the effect of fluvoxamine on p-chloroamphetamine-induced behavior.

Geldof M, Freijer J, van Beijsterveldt L, Vermote PC, Megens AA, Danhof M. Geldof M, et al. Among authors: megens aa. Eur J Pharm Sci. 2007 Nov;32(3):200-8. doi: 10.1016/j.ejps.2007.07.004. Epub 2007 Jul 28. Eur J Pharm Sci. 2007. PMID: 17825539

2

Discovery of a new series of centrally active tricyclic isoxazoles combining serotonin (5-HT) reuptake inhibition with alpha2-adrenoceptor blocking activity.

Andrés JI, Alcázar J, Alonso JM, Alvarez RM, Bakker MH, Biesmans I, Cid JM, De Lucas AI, Fernández J, Font LM, Hens KA, Iturrino L, Lenaerts I, Martínez S, Megens AA, Pastor J, Vermote PC, Steckler T. Andrés JI, et al. Among authors: megens aa. J Med Chem. 2005 Mar 24;48(6):2054-71. doi: 10.1021/jm049619s. J Med Chem. 2005. PMID: 15771448

3

Regional brain distribution of risperidone and its active metabolite 9-hydroxy-risperidone in the rat.

van Beijsterveldt LE, Geerts RJ, Leysen JE, Megens AA, Van den Eynde HM, Meuldermans WE, Heykants JJ. van Beijsterveldt LE, et al. Among authors: megens aa. Psychopharmacology (Berl). 1994 Feb;114(1):53-62. doi: 10.1007/BF02245444. Psychopharmacology (Berl). 1994. PMID: 7531352

4

Pharmacological profile of (2R-trans)-4-[1-[3,5-bis(trifluoromethyl)benzoyl]-2-(phenylmethyl)-4-piperidinyl]-N-(2,6-dimethylphenyl)-1-acetamide (S)-Hydroxybutanedioate (R116301), an orally and centrally active neurokinin-1 receptor antagonist.

Megens AA, Ashton D, Vermeire JC, Vermote PC, Hens KA, Hillen LC, Fransen JF, Mahieu M, Heylen L, Leysen JE, Jurzak MR, Janssens F. Megens AA, et al. J Pharmacol Exp Ther. 2002 Aug;302(2):696-709. doi: 10.1124/jpet.102.034348. J Pharmacol Exp Ther. 2002. PMID: 12130734

5

Preclinical assessment of the feasibility of applying controlled release oral drug delivery to a lead series of atypical antipsychotics.

Eichenbaum G, Pollock-Dove C, Nguyen J, Li S, Evans J, Borghys H, Kennis L, Dong L, van Osdol W, Dai W, Scicinski J, Chen J, Xu Y, Ashton D, Mackie C, Megens A. Eichenbaum G, et al. J Pharm Sci. 2006 Apr;95(4):883-95. doi: 10.1002/jps.20550. J Pharm Sci. 2006. PMID: 16489607

6

Differential interaction of neuroleptics with apomorphine-induced behavior in rats as a function of changing levels of dopamine receptor stimulation.

Megens AA, Hendrickx HM, Lavreysen H, Langlois X. Megens AA, et al. J Pharmacol Exp Ther. 2013 Dec;347(3):681-96. doi: 10.1124/jpet.113.207506. Epub 2013 Sep 26. J Pharmacol Exp Ther. 2013. PMID: 24071734

7

Role of 5-HT(2) receptors in the tryptamine-induced 5-HT syndrome in rats.

Van Oekelen D, Megens A, Meert T, Luyten WH, Leysen JE. Van Oekelen D, et al. Behav Pharmacol. 2002 Jul;13(4):313-8. doi: 10.1097/00008877-200207000-00008. Behav Pharmacol. 2002. PMID: 12218512

8

Functional study of rat 5-HT2A receptors using antisense oligonucleotides.

Van Oekelen D, Megens A, Meert T, Luyten WH, Leysen JE. Van Oekelen D, et al. J Neurochem. 2003 Jun;85(5):1087-100. doi: 10.1046/j.1471-4159.2003.01738.x. J Neurochem. 2003. PMID: 12753068 Free article.

9

Survey on the pharmacodynamics of the new antipsychotic risperidone.

Megens AA, Awouters FH, Schotte A, Meert TF, Dugovic C, Niemegeers CJ, Leysen JE. Megens AA, et al. Psychopharmacology (Berl). 1994 Feb;114(1):9-23. doi: 10.1007/BF02245439. Psychopharmacology (Berl). 1994. PMID: 7531353 Review.

10

Impact of gavage dosing procedure and gastric content on adverse respiratory effects and mortality in rat toxicity studies.

Eichenbaum G, Damsch S, Looszova A, Vandenberghe J, Van den Bulck K, Roels K, Megens A, Knight E, Hillsamer V, Feyen B, Kelley MF, Tonelli A, Lammens L. Eichenbaum G, et al. J Appl Toxicol. 2011 May;31(4):342-54. doi: 10.1002/jat.1592. Epub 2010 Nov 18. J Appl Toxicol. 2011. PMID: 21089156

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