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Nelfinavir, A lead HIV protease inhibitor, is a broad-spectrum, anticancer agent that induces endoplasmic reticulum stress, autophagy, and apoptosis in vitro and in vivo.
Clin Cancer Res. 2007 Sep 1;13(17):5183-94. doi: 10.1158/1078-0432.CCR-07-0161.
Clin Cancer Res. 2007.
PMID: 17785575
Antiretroviral activity of the aminothiol WR1065 against Human Immunodeficiency virus (HIV-1) in vitro and Simian Immunodeficiency virus (SIV) ex vivo.
Poirier MC, Olivero OA, Hardy AW, Franchini G, Borojerdi JP, Walker VE, Walker DM, Shearer GM.
Poirier MC, et al. Among authors: borojerdi jp.
AIDS Res Ther. 2009 Nov 6;6:24. doi: 10.1186/1742-6405-6-24.
AIDS Res Ther. 2009.
PMID: 19895691
Free PMC article.
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Long-term AZT exposure alters the metabolic capacity of cultured human lymphoblastoid cells.
Olivero OA, Vazquez IL, Cooch CC, Ming J, Keller E, Yu M, Borojerdi JP, Braun HM, McKee E, Poirier MC.
Olivero OA, et al. Among authors: borojerdi jp.
Toxicol Sci. 2010 May;115(1):109-17. doi: 10.1093/toxsci/kfq023. Epub 2010 Jan 27.
Toxicol Sci. 2010.
PMID: 20106944
Free PMC article.
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Centrosomal amplification and aneuploidy induced by the antiretroviral drug AZT in hamster and human cells.
Borojerdi JP, Ming J, Cooch C, Ward Y, Semino-Mora C, Yu M, Braun HM, Taylor BJ, Poirier MC, Olivero OA.
Borojerdi JP, et al.
Mutat Res. 2009 Jun 1;665(1-2):67-74. doi: 10.1016/j.mrfmmm.2009.03.004. Epub 2009 Mar 24.
Mutat Res. 2009.
PMID: 19427513
Free PMC article.
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