Dohnal V - Search Results

1

Monooxime reactivators of acetylcholinesterase with (E)-but-2-ene linker: preparation and reactivation of tabun- and paraoxon-inhibited acetylcholinesterase.

Musilek K, Holas O, Jun D, Dohnal V, Gunn-Moore F, Opletalova V, Dolezal M, Kuca K. Musilek K, et al. Among authors: dohnal v. Bioorg Med Chem. 2007 Nov 1;15(21):6733-41. doi: 10.1016/j.bmc.2007.08.002. Epub 2007 Aug 10. Bioorg Med Chem. 2007. PMID: 17764957

2

Synthesis of a novel series of bispyridinium compounds bearing a xylene linker and evaluation of their reactivation activity against chlorpyrifos-inhibited acetylcholinesterase.

Musilek K, Kuca K, Jun D, Dohnal V, Dolezal M. Musilek K, et al. Among authors: dohnal v. J Enzyme Inhib Med Chem. 2005 Oct;20(5):409-15. doi: 10.1080/14756360500179762. J Enzyme Inhib Med Chem. 2005. PMID: 16335048 Free article.

3

Synthesis of asymmetrical bispyridinium compounds bearing cyano-moiety and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase.

Musilek K, Holas O, Kuca K, Jun D, Dohnal V, Dolezal M. Musilek K, et al. Among authors: dohnal v. Bioorg Med Chem Lett. 2006 Nov 1;16(21):5673-6. doi: 10.1016/j.bmcl.2006.08.011. Epub 2006 Aug 24. Bioorg Med Chem Lett. 2006. PMID: 16934462

4

Novel series of bispyridinium compounds bearing a (Z)-but-2-ene linker--synthesis and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase.

Musilek K, Holas O, Kuca K, Jun D, Dohnal V, Opletalova V, Dolezal M. Musilek K, et al. Among authors: dohnal v. Bioorg Med Chem Lett. 2007 Jun 1;17(11):3172-6. doi: 10.1016/j.bmcl.2007.03.025. Epub 2007 Mar 13. Bioorg Med Chem Lett. 2007. PMID: 17383875

5

Synthesis of a novel series of non-symmetrical bispyridinium compounds bearing a xylene linker and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase.

Musilek K, Holas O, Kuca K, Jun D, Dohnal V, Dolezal M. Musilek K, et al. Among authors: dohnal v. J Enzyme Inhib Med Chem. 2007 Aug;22(4):425-32. doi: 10.1080/14756360601164960. J Enzyme Inhib Med Chem. 2007. PMID: 17847708 Free article.

6

Two step synthesis of a non-symmetric acetylcholinesterase reactivator.

Musilek K, Kuca K, Dohnal V, Jun D, Marek J, Koleckar V. Musilek K, et al. Among authors: dohnal v. Molecules. 2007 Aug 7;12(8):1755-61. doi: 10.3390/12081755. Molecules. 2007. PMID: 17960085 Free PMC article.

7

Synthesis of monooxime-monocarbamoyl bispyridinium compounds bearing (E)-but-2-ene linker and evaluation of their reactivation activity against tabun- and paraoxon-inhibited acetylcholinesterase.

Musilek K, Holas O, Kuca K, Jun D, Dohnal V, Opletalova V, Dolezal M. Musilek K, et al. Among authors: dohnal v. J Enzyme Inhib Med Chem. 2008 Feb;23(1):70-6. doi: 10.1080/14756360701383981. J Enzyme Inhib Med Chem. 2008. PMID: 18341256 Free article.

8

Monoquaternary pyridinium salts with modified side chain-synthesis and evaluation on model of tabun- and paraoxon-inhibited acetylcholinesterase.

Musilek K, Kucera J, Jun D, Dohnal V, Opletalova V, Kuca K. Musilek K, et al. Among authors: dohnal v. Bioorg Med Chem. 2008 Sep 1;16(17):8218-23. doi: 10.1016/j.bmc.2008.07.036. Epub 2008 Jul 20. Bioorg Med Chem. 2008. PMID: 18676153

9

Monooxime-monocarbamoyl Bispyridinium Xylene-Linked Reactivators of Acetylcholinesterase-Synthesis, In vitro and Toxicity Evaluation, and Docking Studies.

Musilek K, Holas O, Misik J, Pohanka M, Novotny L, Dohnal V, Opletalova V, Kuca K. Musilek K, et al. Among authors: dohnal v. ChemMedChem. 2010 Feb 1;5(2):247-54. doi: 10.1002/cmdc.200900455. ChemMedChem. 2010. PMID: 20058292

10

Reactivation potency of the acetylcholinesterase reactivator obidoxime is limited.

Kuca K, Musilek K, Pohanka M, Dohnal V, Patocka J. Kuca K, et al. Among authors: dohnal v. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2009 Dec;153(4):259-62. doi: 10.5507/bp.2009.044. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2009. PMID: 20208964 Free article.

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