Sekhar K - Search Results

1

Hedgehog signaling in the murine melanoma microenvironment.

Geng L, Cuneo KC, Cooper MK, Wang H, Sekhar K, Fu A, Hallahan DE. Geng L, et al. Among authors: sekhar k. Angiogenesis. 2007;10(4):259-67. doi: 10.1007/s10456-007-9078-9. Epub 2007 Aug 31. Angiogenesis. 2007. PMID: 17762973

2

Increased expression of nuclear factor E2 p45-related factor 2 (NRF2) in head and neck squamous cell carcinomas.

Stacy DR, Ely K, Massion PP, Yarbrough WG, Hallahan DE, Sekhar KR, Freeman ML. Stacy DR, et al. Among authors: sekhar kr. Head Neck. 2006 Sep;28(9):813-8. doi: 10.1002/hed.20430. Head Neck. 2006. PMID: 16637057

3

Inhibition of mammalian target of rapamycin or apoptotic pathway induces autophagy and radiosensitizes PTEN null prostate cancer cells.

Cao C, Subhawong T, Albert JM, Kim KW, Geng L, Sekhar KR, Gi YJ, Lu B. Cao C, et al. Cancer Res. 2006 Oct 15;66(20):10040-7. doi: 10.1158/0008-5472.CAN-06-0802. Cancer Res. 2006. PMID: 17047067

4

Indolyl-quinuclidinols inhibit ENOX activity and endothelial cell morphogenesis while enhancing radiation-mediated control of tumor vasculature.

Geng L, Rachakonda G, Morré DJ, Morré DM, Crooks PA, Sonar VN, Roti JL, Rogers BE, Greco S, Ye F, Salleng KJ, Sasi S, Freeman ML, Sekhar KR. Geng L, et al. FASEB J. 2009 Sep;23(9):2986-95. doi: 10.1096/fj.09-130005. Epub 2009 Apr 24. FASEB J. 2009. PMID: 19395476 Free PMC article.

5

The novel chemical entity YTR107 inhibits recruitment of nucleophosmin to sites of DNA damage, suppressing repair of DNA double-strand breaks and enhancing radiosensitization.

Sekhar KR, Reddy YT, Reddy PN, Crooks PA, Venkateswaran A, McDonald WH, Geng L, Sasi S, Van Der Waal RP, Roti JL, Salleng KJ, Rachakonda G, Freeman ML. Sekhar KR, et al. Clin Cancer Res. 2011 Oct 15;17(20):6490-9. doi: 10.1158/1078-0432.CCR-11-1054. Epub 2011 Aug 30. Clin Cancer Res. 2011. PMID: 21878537 Free PMC article.

6

Targeting nucleophosmin 1 represents a rational strategy for radiation sensitization.

Sekhar KR, Benamar M, Venkateswaran A, Sasi S, Penthala NR, Crooks PA, Hann SR, Geng L, Balusu R, Abbas T, Freeman ML. Sekhar KR, et al. Int J Radiat Oncol Biol Phys. 2014 Aug 1;89(5):1106-1114. doi: 10.1016/j.ijrobp.2014.04.012. Epub 2014 Jul 8. Int J Radiat Oncol Biol Phys. 2014. PMID: 25035215 Free PMC article.

7

Inhibition of signal transducer and activator of transcription 3 activity results in down-regulation of Survivin following irradiation.

Kim KW, Mutter RW, Cao C, Albert JM, Shinohara ET, Sekhar KR, Lu B. Kim KW, et al. Mol Cancer Ther. 2006 Nov;5(11):2659-65. doi: 10.1158/1535-7163.MCT-06-0261. Mol Cancer Ther. 2006. PMID: 17121912

8

Antiangiogenic properties of substituted (Z)-(±)-2-(N-benzylindol-3-ylmethylene)quinuclidin-3-ol/one analogs and their derivatives.

Venkateswaran A, Reddy YT, Sonar VN, Muthusamy V, Crooks PA, Freeman ML, Sekhar KR. Venkateswaran A, et al. Bioorg Med Chem Lett. 2010 Dec 15;20(24):7323-6. doi: 10.1016/j.bmcl.2010.10.060. Epub 2010 Oct 21. Bioorg Med Chem Lett. 2010. PMID: 21055930 Free PMC article.

9

The NADH oxidase ENOX1, a critical mediator of endothelial cell radiosensitization, is crucial for vascular development.

Venkateswaran A, Sekhar KR, Levic DS, Melville DB, Clark TA, Rybski WM, Walsh AJ, Skala MC, Crooks PA, Knapik EW, Freeman ML. Venkateswaran A, et al. Cancer Res. 2014 Jan 1;74(1):38-43. doi: 10.1158/0008-5472.CAN-13-1981. Epub 2013 Nov 18. Cancer Res. 2014. PMID: 24247717 Free PMC article.

10

Clusterin as a therapeutic target for radiation sensitization in a lung cancer model.

Cao C, Shinohara ET, Li H, Niermann KJ, Kim KW, Sekhar KR, Gleave M, Freeman M, Lu B. Cao C, et al. Int J Radiat Oncol Biol Phys. 2005 Nov 15;63(4):1228-36. doi: 10.1016/j.ijrobp.2005.07.956. Int J Radiat Oncol Biol Phys. 2005. PMID: 16253777

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