Devaraj SG - Search Results

1

Regulation of IRF-3-dependent innate immunity by the papain-like protease domain of the severe acute respiratory syndrome coronavirus.

Devaraj SG, Wang N, Chen Z, Chen Z, Tseng M, Barretto N, Lin R, Peters CJ, Tseng CT, Baker SC, Li K. Devaraj SG, et al. J Biol Chem. 2007 Nov 2;282(44):32208-21. doi: 10.1074/jbc.M704870200. Epub 2007 Aug 30. J Biol Chem. 2007. PMID: 17761676 Free PMC article.

2

Toll-like receptor 3 mediates establishment of an antiviral state against hepatitis C virus in hepatoma cells.

Wang N, Liang Y, Devaraj S, Wang J, Lemon SM, Li K. Wang N, et al. J Virol. 2009 Oct;83(19):9824-34. doi: 10.1128/JVI.01125-09. Epub 2009 Jul 22. J Virol. 2009. PMID: 19625408 Free PMC article.

3

Ubiquitination and proteasomal degradation of interferon regulatory factor-3 induced by Npro from a cytopathic bovine viral diarrhea virus.

Chen Z, Rijnbrand R, Jangra RK, Devaraj SG, Qu L, Ma Y, Lemon SM, Li K. Chen Z, et al. Among authors: devaraj sg. Virology. 2007 Sep 30;366(2):277-92. doi: 10.1016/j.virol.2007.04.023. Epub 2007 May 24. Virology. 2007. PMID: 17531282 Free PMC article.

4

Highly effective combination of LSD1 (KDM1A) antagonist and pan-histone deacetylase inhibitor against human AML cells.

Fiskus W, Sharma S, Shah B, Portier BP, Devaraj SGT, Liu K, Iyer SP, Bearss D, Bhalla KN. Fiskus W, et al. Among authors: devaraj sgt. Leukemia. 2017 Jul;31(7):1658. doi: 10.1038/leu.2017.77. Epub 2017 Mar 21. Leukemia. 2017. PMID: 28322226

5

Synergistic activity of BET protein antagonist-based combinations in mantle cell lymphoma cells sensitive or resistant to ibrutinib.

Sun B, Shah B, Fiskus W, Qi J, Rajapakshe K, Coarfa C, Li L, Devaraj SG, Sharma S, Zhang L, Wang ML, Saenz DT, Krieger S, Bradner JE, Bhalla KN. Sun B, et al. Among authors: devaraj sg. Blood. 2015 Sep 24;126(13):1565-74. doi: 10.1182/blood-2015-04-639542. Epub 2015 Aug 7. Blood. 2015. PMID: 26254443 Free PMC article.

6

HEXIM1 induction is mechanistically involved in mediating anti-AML activity of BET protein bromodomain antagonist.

Devaraj SG, Fiskus W, Shah B, Qi J, Sun B, Iyer SP, Sharma S, Bradner JE, Bhalla KN. Devaraj SG, et al. Leukemia. 2016 Feb;30(2):504-8. doi: 10.1038/leu.2015.142. Epub 2015 Jun 15. Leukemia. 2016. PMID: 26148704 Free PMC article. No abstract available.

7

Pre-clinical efficacy of combined therapy with novel β-catenin antagonist BC2059 and histone deacetylase inhibitor against AML cells.

Fiskus W, Sharma S, Saha S, Shah B, Devaraj SG, Sun B, Horrigan S, Leveque C, Zu Y, Iyer S, Bhalla KN. Fiskus W, et al. Among authors: devaraj sg. Leukemia. 2015 Jun;29(6):1267-78. doi: 10.1038/leu.2014.340. Epub 2014 Dec 8. Leukemia. 2015. PMID: 25482131 Free PMC article.

8

BET protein antagonist JQ1 is synergistically lethal with FLT3 tyrosine kinase inhibitor (TKI) and overcomes resistance to FLT3-TKI in AML cells expressing FLT-ITD.

Fiskus W, Sharma S, Qi J, Shah B, Devaraj SG, Leveque C, Portier BP, Iyer S, Bradner JE, Bhalla KN. Fiskus W, et al. Among authors: devaraj sg. Mol Cancer Ther. 2014 Oct;13(10):2315-27. doi: 10.1158/1535-7163.MCT-14-0258. Epub 2014 Jul 22. Mol Cancer Ther. 2014. PMID: 25053825 Free PMC article.

9

Histone deacetylase inhibitor treatment induces 'BRCAness' and synergistic lethality with PARP inhibitor and cisplatin against human triple negative breast cancer cells.

Ha K, Fiskus W, Choi DS, Bhaskara S, Cerchietti L, Devaraj SG, Shah B, Sharma S, Chang JC, Melnick AM, Hiebert S, Bhalla KN. Ha K, et al. Among authors: devaraj sg. Oncotarget. 2014 Jul 30;5(14):5637-50. doi: 10.18632/oncotarget.2154. Oncotarget. 2014. PMID: 25026298 Free PMC article.

10

Highly effective combination of LSD1 (KDM1A) antagonist and pan-histone deacetylase inhibitor against human AML cells.

Fiskus W, Sharma S, Shah B, Portier BP, Devaraj SG, Liu K, Iyer SP, Bearss D, Bhalla KN. Fiskus W, et al. Among authors: devaraj sg. Leukemia. 2014 Nov;28(11):2155-64. doi: 10.1038/leu.2014.119. Epub 2014 Apr 4. Leukemia. 2014. PMID: 24699304 Free PMC article.

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