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Page 1
Thiophene substituted acylguanidines as BACE1 inhibitors.
Fobare WF, Solvibile WR, Robichaud AJ, Malamas MS, Manas E, Turner J, Hu Y, Wagner E, Chopra R, Cowling R, Jin G, Bard J. Fobare WF, et al. Among authors: solvibile wr. Bioorg Med Chem Lett. 2007 Oct 1;17(19):5353-6. doi: 10.1016/j.bmcl.2007.08.010. Epub 2007 Aug 11. Bioorg Med Chem Lett. 2007. PMID: 17761418
Design and synthesis of aminohydantoins as potent and selective human β-secretase (BACE1) inhibitors with enhanced brain permeability.
Malamas MS, Robichaud A, Erdei J, Quagliato D, Solvibile W, Zhou P, Morris K, Turner J, Wagner E, Fan K, Olland A, Jacobsen S, Reinhart P, Riddell D, Pangalos M. Malamas MS, et al. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6597-605. doi: 10.1016/j.bmcl.2010.09.029. Epub 2010 Sep 15. Bioorg Med Chem Lett. 2010. PMID: 20880704
Benzimidazole- and indole-substituted 1,3'-bipyrrolidine benzamides as histamine H3 receptor antagonists.
Cole DC, Gross JL, Comery TA, Aschmies S, Hirst WD, Kelley C, Kim JI, Kubek K, Ning X, Platt BJ, Robichaud AJ, Solvibile WR, Stock JR, Tawa G, Williams MJ, Ellingboe JW. Cole DC, et al. Among authors: solvibile wr. Bioorg Med Chem Lett. 2010 Feb 1;20(3):1237-40. doi: 10.1016/j.bmcl.2009.11.122. Epub 2009 Dec 4. Bioorg Med Chem Lett. 2010. PMID: 20042333
Synthesis and activity of substituted 4-(indazol-3-yl)phenols as pathway-selective estrogen receptor ligands useful in the treatment of rheumatoid arthritis.
Steffan RJ, Matelan E, Ashwell MA, Moore WJ, Solvibile WR, Trybulski E, Chadwick CC, Chippari S, Kenney T, Eckert A, Borges-Marcucci L, Keith JC, Xu Z, Mosyak L, Harnish DC. Steffan RJ, et al. Among authors: solvibile wr. J Med Chem. 2004 Dec 16;47(26):6435-8. doi: 10.1021/jm049194+. J Med Chem. 2004. PMID: 15588074
Control of chronic inflammation with pathway selective estrogen receptor ligands.
Steffan RJ, Matelan E, Ashwell MA, Moore WJ, Solvibile WR, Trybulski E, Chadwick CC, Chippari S, Kenney T, Winneker RC, Eckert A, Borges-Marcucci L, Adelman SJ, Xu Z, Mosyak L, Harnish DC. Steffan RJ, et al. Among authors: solvibile wr. Curr Top Med Chem. 2006;6(2):103-11. doi: 10.2174/156802606775270279. Curr Top Med Chem. 2006. PMID: 16454762 Review.