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Tip60 is a haplo-insufficient tumour suppressor required for an oncogene-induced DNA damage response.
Gorrini C, Squatrito M, Luise C, Syed N, Perna D, Wark L, Martinato F, Sardella D, Verrecchia A, Bennett S, Confalonieri S, Cesaroni M, Marchesi F, Gasco M, Scanziani E, Capra M, Mai S, Nuciforo P, Crook T, Lough J, Amati B. Gorrini C, et al. Among authors: squatrito m. Nature. 2007 Aug 30;448(7157):1063-7. doi: 10.1038/nature06055. Nature. 2007. PMID: 17728759
LIF regulates CXCL9 in tumor-associated macrophages and prevents CD8+ T cell tumor-infiltration impairing anti-PD1 therapy.
Pascual-García M, Bonfill-Teixidor E, Planas-Rigol E, Rubio-Perez C, Iurlaro R, Arias A, Cuartas I, Sala-Hojman A, Escudero L, Martínez-Ricarte F, Huber-Ruano I, Nuciforo P, Pedrosa L, Marques C, Braña I, Garralda E, Vieito M, Squatrito M, Pineda E, Graus F, Espejo C, Sahuquillo J, Tabernero J, Seoane J. Pascual-García M, et al. Among authors: squatrito m. Nat Commun. 2019 Jun 11;10(1):2416. doi: 10.1038/s41467-019-10369-9. Nat Commun. 2019. PMID: 31186412 Free PMC article.
Clonally expanded CD8 T cells characterize amyotrophic lateral sclerosis-4.
Campisi L, Chizari S, Ho JSY, Gromova A, Arnold FJ, Mosca L, Mei X, Fstkchyan Y, Torre D, Beharry C, Garcia-Forn M, Jiménez-Alcázar M, Korobeynikov VA, Prazich J, Fayad ZA, Seldin MM, De Rubeis S, Bennett CL, Ostrow LW, Lunetta C, Squatrito M, Byun M, Shneider NA, Jiang N, La Spada AR, Marazzi I. Campisi L, et al. Among authors: squatrito m. Nature. 2022 Jun;606(7916):945-952. doi: 10.1038/s41586-022-04844-5. Epub 2022 Jun 22. Nature. 2022. PMID: 35732742 Free PMC article.
EGFR feedback-inhibition by Ran-binding protein 6 is disrupted in cancer.
Oldrini B, Hsieh WY, Erdjument-Bromage H, Codega P, Carro MS, Curiel-García A, Campos C, Pourmaleki M, Grommes C, Vivanco I, Rohle D, Bielski CM, Taylor BS, Hollmann TJ, Rosenblum M, Tempst P, Blenis J, Squatrito M, Mellinghoff IK. Oldrini B, et al. Among authors: squatrito m. Nat Commun. 2017 Dec 11;8(1):2035. doi: 10.1038/s41467-017-02185-w. Nat Commun. 2017. PMID: 29229958 Free PMC article.
Dual mode of degradation of Cdc25 A phosphatase.
Donzelli M, Squatrito M, Ganoth D, Hershko A, Pagano M, Draetta GF. Donzelli M, et al. Among authors: squatrito m. EMBO J. 2002 Sep 16;21(18):4875-84. doi: 10.1093/emboj/cdf491. EMBO J. 2002. PMID: 12234927 Free PMC article.
Author Correction: Clonally expanded CD8 T cells characterize amyotrophic lateral sclerosis-4.
Campisi L, Chizari S, Ho JSY, Gromova A, Arnold FJ, Mosca L, Mei X, Fstkchyan Y, Torre D, Beharry C, Garcia-Forn M, Jiménez-Alcázar M, Korobeynikov VA, Prazich J, Fayad ZA, Seldin MM, De Rubeis S, Bennett CL, Ostrow LW, Lunetta C, Squatrito M, Byun M, Shneider NA, Jiang N, La Spada AR, Marazzi I. Campisi L, et al. Among authors: squatrito m. Nature. 2022 Aug;608(7924):E34. doi: 10.1038/s41586-022-05184-0. Nature. 2022. PMID: 35945277 Free PMC article. No abstract available.
The Irradiated Brain Microenvironment Supports Glioma Stemness and Survival via Astrocyte-Derived Transglutaminase 2.
Berg TJ, Marques C, Pantazopoulou V, Johansson E, von Stedingk K, Lindgren D, Jeannot P, Pietras EJ, Bergström T, Swartling FJ, Governa V, Bengzon J, Belting M, Axelson H, Squatrito M, Pietras A. Berg TJ, et al. Among authors: squatrito m. Cancer Res. 2021 Apr 15;81(8):2101-2115. doi: 10.1158/0008-5472.CAN-20-1785. Epub 2021 Jan 22. Cancer Res. 2021. PMID: 33483373
MGMT genomic rearrangements contribute to chemotherapy resistance in gliomas.
Oldrini B, Vaquero-Siguero N, Mu Q, Kroon P, Zhang Y, Galán-Ganga M, Bao Z, Wang Z, Liu H, Sa JK, Zhao J, Kim H, Rodriguez-Perales S, Nam DH, Verhaak RGW, Rabadan R, Jiang T, Wang J, Squatrito M. Oldrini B, et al. Among authors: squatrito m. Nat Commun. 2020 Aug 4;11(1):3883. doi: 10.1038/s41467-020-17717-0. Nat Commun. 2020. PMID: 32753598 Free PMC article.
50 results