Sygusch J - Search Results

1

Stereospecific proton transfer by a mobile catalyst in mammalian fructose-1,6-bisphosphate aldolase.

St-Jean M, Sygusch J. St-Jean M, et al. Among authors: sygusch j. J Biol Chem. 2007 Oct 19;282(42):31028-37. doi: 10.1074/jbc.M704968200. Epub 2007 Aug 29. J Biol Chem. 2007. PMID: 17728250 Free article.

2

High resolution reaction intermediates of rabbit muscle fructose-1,6-bisphosphate aldolase: substrate cleavage and induced fit.

St-Jean M, Lafrance-Vanasse J, Liotard B, Sygusch J. St-Jean M, et al. Among authors: sygusch j. J Biol Chem. 2005 Jul 22;280(29):27262-70. doi: 10.1074/jbc.M502413200. Epub 2005 May 3. J Biol Chem. 2005. PMID: 15870069 Free article.

3

A hydrophobic pocket in the active site of glycolytic aldolase mediates interactions with Wiskott-Aldrich syndrome protein.

St-Jean M, Izard T, Sygusch J. St-Jean M, et al. Among authors: sygusch j. J Biol Chem. 2007 May 11;282(19):14309-15. doi: 10.1074/jbc.M611505200. Epub 2007 Feb 27. J Biol Chem. 2007. PMID: 17329259 Free article.

4

Charge stabilization and entropy reduction of central lysine residues in fructose-bisphosphate aldolase.

St-Jean M, Blonski C, Sygusch J. St-Jean M, et al. Among authors: sygusch j. Biochemistry. 2009 Jun 2;48(21):4528-37. doi: 10.1021/bi8021558. Biochemistry. 2009. PMID: 19354220

5

A conserved glutamate residue exhibits multifunctional catalytic roles in D-fructose-1,6-bisphosphate aldolases.

Maurady A, Zdanov A, de Moissac D, Beaudry D, Sygusch J. Maurady A, et al. Among authors: sygusch j. J Biol Chem. 2002 Mar 15;277(11):9474-83. doi: 10.1074/jbc.M107600200. Epub 2002 Jan 4. J Biol Chem. 2002. PMID: 11779856 Free article.

6

Isomer activation controls stereospecificity of class I fructose-1,6-bisphosphate aldolases.

Heron PW, Sygusch J. Heron PW, et al. Among authors: sygusch j. J Biol Chem. 2017 Dec 1;292(48):19849-19860. doi: 10.1074/jbc.M117.811034. Epub 2017 Sep 27. J Biol Chem. 2017. PMID: 28972169 Free PMC article.

7

Active site remodeling during the catalytic cycle in metal-dependent fructose-1,6-bisphosphate aldolases.

Jacques B, Coinçon M, Sygusch J. Jacques B, et al. Among authors: sygusch j. J Biol Chem. 2018 May 18;293(20):7737-7753. doi: 10.1074/jbc.RA117.001098. Epub 2018 Mar 28. J Biol Chem. 2018. PMID: 29593097 Free PMC article.

8

Structure of a class I tagatose-1,6-bisphosphate aldolase: investigation into an apparent loss of stereospecificity.

LowKam C, Liotard B, Sygusch J. LowKam C, et al. Among authors: sygusch j. J Biol Chem. 2010 Jul 2;285(27):21143-52. doi: 10.1074/jbc.M109.080358. Epub 2010 Apr 28. J Biol Chem. 2010. PMID: 20427286 Free PMC article.

9

Crystal structure of reaction intermediates in pyruvate class II aldolase: substrate cleavage, enolate stabilization, and substrate specificity.

Coincon M, Wang W, Sygusch J, Seah SY. Coincon M, et al. Among authors: sygusch j. J Biol Chem. 2012 Oct 19;287(43):36208-21. doi: 10.1074/jbc.M112.400705. Epub 2012 Aug 20. J Biol Chem. 2012. PMID: 22908224 Free PMC article.

10

Carboxyl terminus region modulates catalytic activity of recombinant maize aldolase.

Berthiaume L, Loisel TP, Sygusch J. Berthiaume L, et al. Among authors: sygusch j. J Biol Chem. 1991 Sep 15;266(26):17099-105. J Biol Chem. 1991. PMID: 1894606 Free article.

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