Hemsley K - Search Results

1

Functional correction of CNS lesions in an MPS-IIIA mouse model by intracerebral AAV-mediated delivery of sulfamidase and SUMF1 genes.

Fraldi A, Hemsley K, Crawley A, Lombardi A, Lau A, Sutherland L, Auricchio A, Ballabio A, Hopwood JJ. Fraldi A, et al. Among authors: hemsley k. Hum Mol Genet. 2007 Nov 15;16(22):2693-702. doi: 10.1093/hmg/ddm223. Epub 2007 Aug 27. Hum Mol Genet. 2007. PMID: 17725987

2

In vitro characterization of genetically modified embryonic stem cells as a therapy for murine mucopolysaccharidosis type IIIA.

Lau AA, Hemsley KM, Meedeniya A, Hopwood JJ. Lau AA, et al. Mol Genet Metab. 2004 Feb;81(2):86-95. doi: 10.1016/j.ymgme.2003.11.007. Mol Genet Metab. 2004. PMID: 14741188

3

Intracerebral injection of sulfamidase delays neuropathology in murine MPS-IIIA.

Savas PS, Hemsley KM, Hopwood JJ. Savas PS, et al. Mol Genet Metab. 2004 Aug;82(4):273-85. doi: 10.1016/j.ymgme.2004.05.005. Mol Genet Metab. 2004. PMID: 15308125

4

Development of motor deficits in a murine model of mucopolysaccharidosis type IIIA (MPS-IIIA).

Hemsley KM, Hopwood JJ. Hemsley KM, et al. Behav Brain Res. 2005 Mar 30;158(2):191-9. doi: 10.1016/j.bbr.2004.08.019. Behav Brain Res. 2005. PMID: 15698885

5

Survival and engraftment of mouse embryonic stem cell-derived implants in the guinea pig brain.

Robinson AJ, Meedeniya AC, Hemsley KM, Auclair D, Crawley AC, Hopwood JJ. Robinson AJ, et al. Among authors: hemsley km. Neurosci Res. 2005 Oct;53(2):161-8. doi: 10.1016/j.neures.2005.06.010. Neurosci Res. 2005. PMID: 16023750

6

Validation of a heparan sulfate-derived disaccharide as a marker of accumulation in murine mucopolysaccharidosis type IIIA.

King B, Savas P, Fuller M, Hopwood J, Hemsley K. King B, et al. Among authors: hemsley k. Mol Genet Metab. 2006 Feb;87(2):107-12. doi: 10.1016/j.ymgme.2005.09.026. Epub 2005 Dec 13. Mol Genet Metab. 2006. PMID: 16352454

7

Characterization of a C57BL/6 congenic mouse strain of mucopolysaccharidosis type IIIA.

Crawley AC, Gliddon BL, Auclair D, Brodie SL, Hirte C, King BM, Fuller M, Hemsley KM, Hopwood JJ. Crawley AC, et al. Brain Res. 2006 Aug 9;1104(1):1-17. doi: 10.1016/j.brainres.2006.05.079. Epub 2006 Jul 7. Brain Res. 2006. PMID: 16828069

8

Directed differentiation and characterization of genetically modified embryonic stem cells for therapy.

Lau AA, Hemsley KM, Meedeniya A, Robinson AJ, Hopwood JJ. Lau AA, et al. Methods Mol Biol. 2006;329:471-84. doi: 10.1385/1-59745-037-5:471. Methods Mol Biol. 2006. PMID: 16846011

9

Injection of recombinant human sulfamidase into the CSF via the cerebellomedullary cistern in MPS IIIA mice.

Hemsley KM, King B, Hopwood JJ. Hemsley KM, et al. Mol Genet Metab. 2007 Mar;90(3):313-28. doi: 10.1016/j.ymgme.2006.10.005. Epub 2006 Dec 12. Mol Genet Metab. 2007. PMID: 17166757

10

Behavioural characterisation of the alpha-mannosidosis guinea pig.

Robinson AJ, Crawley AC, Auclair D, Weston PF, Hirte C, Hemsley KM, Hopwood JJ. Robinson AJ, et al. Among authors: hemsley km. Behav Brain Res. 2008 Jan 25;186(2):176-84. doi: 10.1016/j.bbr.2007.08.005. Epub 2007 Aug 10. Behav Brain Res. 2008. PMID: 17889945

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