Horwitz J - Search Results

1

Degradation of C-terminal truncated alpha A-crystallins by the ubiquitin-proteasome pathway.

Zhang X, Dudek EJ, Liu B, Ding L, Fernandes AF, Liang JJ, Horwitz J, Taylor A, Shang F. Zhang X, et al. Among authors: horwitz j. Invest Ophthalmol Vis Sci. 2007 Sep;48(9):4200-8. doi: 10.1167/iovs.07-0196. Invest Ophthalmol Vis Sci. 2007. PMID: 17724207 Free PMC article.

2

Oligomerization with wt αA- and αB-crystallins reduces proteasome-mediated degradation of C-terminally truncated αA-crystallin.

Wu M, Zhang X, Bian Q, Taylor A, Liang JJ, Ding L, Horwitz J, Shang F. Wu M, et al. Among authors: horwitz j. Invest Ophthalmol Vis Sci. 2012 May 4;53(6):2541-50. doi: 10.1167/iovs.11-9147. Invest Ophthalmol Vis Sci. 2012. PMID: 22427585 Free PMC article.

3

Mechanism of cataract formation in alphaA-crystallin Y118D mutation.

Huang Q, Ding L, Phan KB, Cheng C, Xia CH, Gong X, Horwitz J. Huang Q, et al. Among authors: horwitz j. Invest Ophthalmol Vis Sci. 2009 Jun;50(6):2919-26. doi: 10.1167/iovs.08-3070. Epub 2009 Jan 17. Invest Ophthalmol Vis Sci. 2009. PMID: 19151380 Free PMC article.

4

Altered chaperone-like activity of alpha-crystallins promotes cataractogenesis.

Cheng C, Xia CH, Huang Q, Ding L, Horwitz J, Gong X. Cheng C, et al. Among authors: horwitz j. J Biol Chem. 2010 Dec 24;285(52):41187-93. doi: 10.1074/jbc.M110.154534. Epub 2010 Oct 19. J Biol Chem. 2010. PMID: 20959464 Free PMC article.

5

Zebrafish alpha-crystallins: protein structure and chaperone-like activity compared to their mammalian orthologs.

Dahlman JM, Margot KL, Ding L, Horwitz J, Posner M. Dahlman JM, et al. Among authors: horwitz j. Mol Vis. 2005 Jan 26;11:88-96. Mol Vis. 2005. PMID: 15692462 Free article.

6

Crystallin {gamma}B-I4F mutant protein binds to {alpha}-crystallin and affects lens transparency.

Liu H, Du X, Wang M, Huang Q, Ding L, McDonald HW, Yates JR 3rd, Beutler B, Horwitz J, Gong X. Liu H, et al. Among authors: horwitz j. J Biol Chem. 2005 Jul 1;280(26):25071-8. doi: 10.1074/jbc.M502490200. Epub 2005 May 4. J Biol Chem. 2005. PMID: 15878859 Free article.

7

The native oligomeric organization of alpha-crystallin, is it necessary for its chaperone function?

Horwitz J, Huang Q, Ding L. Horwitz J, et al. Exp Eye Res. 2004 Dec;79(6):817-21. doi: 10.1016/j.exer.2004.05.007. Exp Eye Res. 2004. PMID: 15642318

8

Vertebrate-like betagamma-crystallins in the ocular lenses of a copepod.

Cohen JH, Piatigorsky J, Ding L, Colley NJ, Ward R, Horwitz J. Cohen JH, et al. Among authors: horwitz j. J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2005 Mar;191(3):291-8. doi: 10.1007/s00359-004-0594-4. Epub 2005 Feb 9. J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2005. PMID: 15702356

9

Crystal structures of truncated alphaA and alphaB crystallins reveal structural mechanisms of polydispersity important for eye lens function.

Laganowsky A, Benesch JL, Landau M, Ding L, Sawaya MR, Cascio D, Huang Q, Robinson CV, Horwitz J, Eisenberg D. Laganowsky A, et al. Among authors: horwitz j. Protein Sci. 2010 May;19(5):1031-43. doi: 10.1002/pro.380. Protein Sci. 2010. PMID: 20440841 Free PMC article.

10

Lens alpha-crystallin: function and structure.

Horwitz J, Bova MP, Ding LL, Haley DA, Stewart PL. Horwitz J, et al. Eye (Lond). 1999 Jun;13 ( Pt 3b):403-8. doi: 10.1038/eye.1999.114. Eye (Lond). 1999. PMID: 10627817

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