Khani SC - Search Results

1

AAV-mediated expression targeting of rod and cone photoreceptors with a human rhodopsin kinase promoter.

Khani SC, Pawlyk BS, Bulgakov OV, Kasperek E, Young JE, Adamian M, Sun X, Smith AJ, Ali RR, Li T. Khani SC, et al. Invest Ophthalmol Vis Sci. 2007 Sep;48(9):3954-61. doi: 10.1167/iovs.07-0257. Invest Ophthalmol Vis Sci. 2007. PMID: 17724172

2

A short, highly active photoreceptor-specific enhancer/promoter region upstream of the human rhodopsin kinase gene.

Young JE, Vogt T, Gross KW, Khani SC. Young JE, et al. Among authors: khani sc. Invest Ophthalmol Vis Sci. 2003 Sep;44(9):4076-85. doi: 10.1167/iovs.03-0197. Invest Ophthalmol Vis Sci. 2003. PMID: 12939331

3

Conserved structure and spatiotemporal function of the compact rhodopsin kinase (GRK1) enhancer/promoter.

Young JE, Gross KW, Khani SC. Young JE, et al. Among authors: khani sc. Mol Vis. 2005 Dec 7;11:1041-51. Mol Vis. 2005. PMID: 16357827 Free article.

4

Conserved interactions of a compact highly active enhancer/promoter upstream of the rhodopsin kinase (GRK1) gene.

Young JE, Kasperek EM, Vogt TM, Lis A, Khani SC. Young JE, et al. Among authors: khani sc. Genomics. 2007 Aug;90(2):236-48. doi: 10.1016/j.ygeno.2007.03.004. Epub 2007 May 23. Genomics. 2007. PMID: 17524610 Free article.

5

Effect of g protein-coupled receptor kinase 1 (Grk1) overexpression on rod photoreceptor cell viability.

Whitcomb T, Sakurai K, Brown BM, Young JE, Sheflin L, Dlugos C, Craft CM, Kefalov VJ, Khani SC. Whitcomb T, et al. Among authors: khani sc. Invest Ophthalmol Vis Sci. 2010 Mar;51(3):1728-37. doi: 10.1167/iovs.09-4499. Epub 2009 Oct 15. Invest Ophthalmol Vis Sci. 2010. PMID: 19834036 Free PMC article.

6

Variation in rhodopsin kinase expression alters the dim flash response shut off and the light adaptation in rod photoreceptors.

Sakurai K, Young JE, Kefalov VJ, Khani SC. Sakurai K, et al. Among authors: khani sc. Invest Ophthalmol Vis Sci. 2011 Aug 29;52(9):6793-800. doi: 10.1167/iovs.11-7158. Invest Ophthalmol Vis Sci. 2011. PMID: 21474765 Free PMC article.

7

Photoreceptor rescue by an abbreviated human RPGR gene in a murine model of X-linked retinitis pigmentosa.

Pawlyk BS, Bulgakov OV, Sun X, Adamian M, Shu X, Smith AJ, Berson EL, Ali RR, Khani S, Wright AF, Sandberg MA, Li T. Pawlyk BS, et al. Gene Ther. 2016 Feb;23(2):196-204. doi: 10.1038/gt.2015.93. Epub 2015 Sep 8. Gene Ther. 2016. PMID: 26348595 Free PMC article.

8

Gene therapy with a promoter targeting both rods and cones rescues retinal degeneration caused by AIPL1 mutations.

Sun X, Pawlyk B, Xu X, Liu X, Bulgakov OV, Adamian M, Sandberg MA, Khani SC, Tan MH, Smith AJ, Ali RR, Li T. Sun X, et al. Among authors: khani sc. Gene Ther. 2010 Jan;17(1):117-31. doi: 10.1038/gt.2009.104. Epub 2009 Aug 27. Gene Ther. 2010. Retraction in: Gene Ther. 2024 Nov 15. doi: 10.1038/s41434-024-00505-6 PMID: 19710705 Free PMC article. Retracted.

9

Replacement gene therapy with a human RPGRIP1 sequence slows photoreceptor degeneration in a murine model of Leber congenital amaurosis.

Pawlyk BS, Bulgakov OV, Liu X, Xu X, Adamian M, Sun X, Khani SC, Berson EL, Sandberg MA, Li T. Pawlyk BS, et al. Among authors: khani sc. Hum Gene Ther. 2010 Aug;21(8):993-1004. doi: 10.1089/hum.2009.218. Hum Gene Ther. 2010. PMID: 20384479 Free PMC article.

10

Late-onset autosomal dominant macular dystrophy with choroidal neovascularization and nonexudative maculopathy associated with mutation in the RDS gene.

Khani SC, Karoukis AJ, Young JE, Ambasudhan R, Burch T, Stockton R, Lewis RA, Sullivan LS, Daiger SP, Reichel E, Ayyagari R. Khani SC, et al. Invest Ophthalmol Vis Sci. 2003 Aug;44(8):3570-7. doi: 10.1167/iovs.02-1287. Invest Ophthalmol Vis Sci. 2003. PMID: 12882809 Free PMC article.

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