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Metabotropic glutamate receptor 5 (mGluR5)-mediated phosphoinositide hydrolysis and NMDA-potentiating effects are blunted in the striatum of aged rats: a possible additional mechanism in striatal senescence.
Domenici MR, Pintor A, Potenza RL, Gaudi S, Grò MC, Passarelli F, Reggio R, Galluzzo M, Massotti M, Popoli P. Domenici MR, et al. Among authors: potenza rl. Eur J Neurosci. 2003 May;17(10):2047-55. doi: 10.1046/j.1460-9568.2003.02649.x. Eur J Neurosci. 2003. PMID: 12786971
Neuroprotective effects of the mGlu5R antagonist MPEP towards quinolinic acid-induced striatal toxicity: involvement of pre- and post-synaptic mechanisms and lack of direct NMDA blocking activity.
Popoli P, Pintor A, Tebano MT, Frank C, Pepponi R, Nazzicone V, Grieco R, Pèzzola A, Reggio R, Minghetti L, De Berardinis MA, Martire A, Potenza RL, Domenici MR, Massotti M. Popoli P, et al. Among authors: potenza rl. J Neurochem. 2004 Jun;89(6):1479-89. doi: 10.1111/j.1471-4159.2004.02448.x. J Neurochem. 2004. PMID: 15189351 Free article.
Chronic treatment with the mGlu5R antagonist MPEP reduces the functional effects of the mGlu5R agonist CHPG in the striatum of 6-hydroxydopamine-lesioned rats: possible relevance to the effects of mGlu5R blockade in Parkinson's disease.
Domenici MR, Potenza RL, Martire A, Coccurello R, Pèzzola A, Reggio R, Tebano MT, Popoli P. Domenici MR, et al. Among authors: potenza rl. J Neurosci Res. 2005 Jun 1;80(5):646-54. doi: 10.1002/jnr.20489. J Neurosci Res. 2005. PMID: 15880742
Effects of the adenosine A2A receptor antagonist SCH 58621 on cyclooxygenase-2 expression, glial activation, and brain-derived neurotrophic factor availability in a rat model of striatal neurodegeneration.
Minghetti L, Greco A, Potenza RL, Pezzola A, Blum D, Bantubungi K, Popoli P. Minghetti L, et al. Among authors: potenza rl. J Neuropathol Exp Neurol. 2007 May;66(5):363-71. doi: 10.1097/nen.0b013e3180517477. J Neuropathol Exp Neurol. 2007. PMID: 17483693
38 results