Liu G - Search Results

1

Structure-activity relationships of 3,4-dihydro-1H-quinazolin-2-one derivatives as potential CDK5 inhibitors.

Rzasa RM, Kaller MR, Liu G, Magal E, Nguyen TT, Osslund TD, Powers D, Santora VJ, Viswanadhan VN, Wang HL, Xiong X, Zhong W, Norman MH. Rzasa RM, et al. Among authors: liu g. Bioorg Med Chem. 2007 Oct 15;15(20):6574-95. doi: 10.1016/j.bmc.2007.07.005. Epub 2007 Jul 25. Bioorg Med Chem. 2007. PMID: 17697781

2

Discovery and structure-activity relationship of oxalylarylaminobenzoic acids as inhibitors of protein tyrosine phosphatase 1B.

Liu G, Szczepankiewicz BG, Pei Z, Janowick DA, Xin Z, Hajduk PJ, Abad-Zapatero C, Liang H, Hutchins CW, Fesik SW, Ballaron SJ, Stashko MA, Lubben T, Mika AK, Zinker BA, Trevillyan JM, Jirousek MR. Liu G, et al. J Med Chem. 2003 May 22;46(11):2093-103. doi: 10.1021/jm0205696. J Med Chem. 2003. PMID: 12747781

3

Isoxazole carboxylic acids as protein tyrosine phosphatase 1B (PTP1B) inhibitors.

Zhao H, Liu G, Xin Z, Serby MD, Pei Z, Szczepankiewicz BG, Hajduk PJ, Abad-Zapatero C, Hutchins CW, Lubben TH, Ballaron SJ, Haasch DL, Kaszubska W, Rondinone CM, Trevillyan JM, Jirousek MR. Zhao H, et al. Among authors: liu g. Bioorg Med Chem Lett. 2004 Nov 15;14(22):5543-6. doi: 10.1016/j.bmcl.2004.08.063. Bioorg Med Chem Lett. 2004. PMID: 15482920

4

Synthesis and structure-activity relationships of isoxazole carboxamides as growth hormone secretagogue receptor antagonists.

Xin Z, Zhao H, Serby MD, Liu B, Schaefer VG, Falls DH, Kaszubska W, Colins CA, Sham HL, Liu G. Xin Z, et al. Among authors: liu b, liu g. Bioorg Med Chem Lett. 2005 Feb 15;15(4):1201-4. doi: 10.1016/j.bmcl.2004.11.075. Bioorg Med Chem Lett. 2005. PMID: 15686942

5

Structure-activity relationship studies on tetralin carboxamide growth hormone secretagogue receptor antagonists.

Zhao H, Xin Z, Patel JR, Nelson LT, Liu B, Szczepankiewicz BG, Schaefer VG, Falls HD, Kaszubska W, Collins CA, Sham HL, Liu G. Zhao H, et al. Among authors: liu b, liu g. Bioorg Med Chem Lett. 2005 Apr 1;15(7):1825-8. doi: 10.1016/j.bmcl.2005.02.026. Bioorg Med Chem Lett. 2005. PMID: 15780615

6

Synthesis and SAR of 1,9-dihydro-9-hydroxypyrazolo[3,4-b]quinolin-4-ones as novel, selective c-Jun N-terminal kinase inhibitors.

Liu M, Xin Z, Clampit JE, Wang S, Gum RJ, Haasch DL, Trevillyan JM, Abad-Zapatero C, Fry EH, Sham HL, Liu G. Liu M, et al. Among authors: liu g. Bioorg Med Chem Lett. 2006 May 15;16(10):2590-4. doi: 10.1016/j.bmcl.2006.02.046. Epub 2006 Mar 9. Bioorg Med Chem Lett. 2006. PMID: 16527482

7

Aminopyridine-based c-Jun N-terminal kinase inhibitors with cellular activity and minimal cross-kinase activity.

Szczepankiewicz BG, Kosogof C, Nelson LT, Liu G, Liu B, Zhao H, Serby MD, Xin Z, Liu M, Gum RJ, Haasch DL, Wang S, Clampit JE, Johnson EF, Lubben TH, Stashko MA, Olejniczak ET, Sun C, Dorwin SA, Haskins K, Abad-Zapatero C, Fry EH, Hutchins CW, Sham HL, Rondinone CM, Trevillyan JM. Szczepankiewicz BG, et al. Among authors: liu m, liu b, liu g. J Med Chem. 2006 Jun 15;49(12):3563-80. doi: 10.1021/jm060199b. J Med Chem. 2006. PMID: 16759099

8

Synthesis and structure-activity relationships of N-{3-[2-(4-alkoxyphenoxy)thiazol-5-yl]-1- methylprop-2-ynyl}carboxy derivatives as selective acetyl-CoA carboxylase 2 inhibitors.

Gu YG, Weitzberg M, Clark RF, Xu X, Li Q, Zhang T, Hansen TM, Liu G, Xin Z, Wang X, Wang R, McNally T, Zinker BA, Frevert EU, Camp HS, Beutel BA, Sham HL. Gu YG, et al. Among authors: liu g. J Med Chem. 2006 Jun 29;49(13):3770-3. doi: 10.1021/jm060484v. J Med Chem. 2006. PMID: 16789734

9

Aminopyridine carboxamides as c-Jun N-terminal kinase inhibitors: targeting the gatekeeper residue and beyond.

Liu G, Zhao H, Liu B, Xin Z, Liu M, Kosogof C, Szczepankiewicz BG, Wang S, Clampit JE, Gum RJ, Haasch DL, Trevillyan JM, Sham HL. Liu G, et al. Among authors: liu m, liu b. Bioorg Med Chem Lett. 2006 Nov 15;16(22):5723-30. doi: 10.1016/j.bmcl.2006.08.097. Epub 2006 Sep 12. Bioorg Med Chem Lett. 2006. PMID: 16971120

10

Structure-activity relationships for a novel series of thiazolyl phenyl ether derivatives exhibiting potent and selective acetyl-CoA carboxylase 2 inhibitory activity.

Clark RF, Zhang T, Xin Z, Liu G, Wang Y, Hansen TM, Wang X, Wang R, Zhang X, Frevert EU, Camp HS, Beutel BA, Sham HL, Gu YG. Clark RF, et al. Among authors: liu g. Bioorg Med Chem Lett. 2006 Dec 1;16(23):6078-81. doi: 10.1016/j.bmcl.2006.08.100. Epub 2006 Sep 14. Bioorg Med Chem Lett. 2006. PMID: 16973360

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