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Characterization and structural analysis of novel mutations in human immunodeficiency virus type 1 reverse transcriptase involved in the regulation of resistance to nonnucleoside inhibitors.
Ceccherini-Silberstein F, Svicher V, Sing T, Artese A, Santoro MM, Forbici F, Bertoli A, Alcaro S, Palamara G, d'Arminio Monforte A, Balzarini J, Antinori A, Lengauer T, Perno CF. Ceccherini-Silberstein F, et al. Among authors: balzarini j. J Virol. 2007 Oct;81(20):11507-19. doi: 10.1128/JVI.00303-07. Epub 2007 Aug 8. J Virol. 2007. PMID: 17686836 Free PMC article.
High sequence conservation of human immunodeficiency virus type 1 reverse transcriptase under drug pressure despite the continuous appearance of mutations.
Ceccherini-Silberstein F, Gago F, Santoro M, Gori C, Svicher V, Rodríguez-Barrios F, d'Arrigo R, Ciccozzi M, Bertoli A, d'Arminio Monforte A, Balzarini J, Antinori A, Perno CF. Ceccherini-Silberstein F, et al. Among authors: balzarini j. J Virol. 2005 Aug;79(16):10718-29. doi: 10.1128/JVI.79.16.10718-10729.2005. J Virol. 2005. PMID: 16051864 Free PMC article.
Different evolution of genotypic resistance profiles to emtricitabine versus lamivudine in tenofovir-containing regimens.
Svicher V, Alteri C, Artese A, Forbici F, Santoro MM, Schols D, Van Laethem K, Alcaro S, Costa G, Tommasi C, Zaccarelli M, Narciso P, Antinori A, Ceccherini-Silberstein F, Balzarini J, Perno CF. Svicher V, et al. Among authors: balzarini j. J Acquir Immune Defic Syndr. 2010 Nov;55(3):336-44. doi: 10.1097/QAI.0b013e3181e6763f. J Acquir Immune Defic Syndr. 2010. PMID: 20739898
Limited development and progression of resistance of HIV-1 to the nucleoside analogue reverse transcriptase inhibitor lamivudine in human primary macrophages.
Aquaro S, Svicher V, Ceccherini-Silberstein F, Cenci A, Marcuccilli F, Giannella S, Marcon L, Caliò R, Balzarini J, Perno CF. Aquaro S, et al. Among authors: balzarini j. J Antimicrob Chemother. 2005 Jun;55(6):872-8. doi: 10.1093/jac/dki104. Epub 2005 Apr 21. J Antimicrob Chemother. 2005. PMID: 15845785
Therapeutic strategies towards HIV-1 infection in macrophages.
Perno CF, Svicher V, Schols D, Pollicita M, Balzarini J, Aquaro S. Perno CF, et al. Among authors: balzarini j. Antiviral Res. 2006 Sep;71(2-3):293-300. doi: 10.1016/j.antiviral.2006.05.015. Epub 2006 Jun 9. Antiviral Res. 2006. PMID: 16806514 Review.
Exploitation of the low fidelity of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase and the nucleotide composition bias in the HIV-1 genome to alter the drug resistance development of HIV.
Balzarini J, Camarasa MJ, Pérez-Pérez MJ, San-Félix A, Velázquez S, Perno CF, De Clercq E, Anderson JN, Karlsson A. Balzarini J, et al. J Virol. 2001 Jul;75(13):5772-7. doi: 10.1128/JVI.75.13.5772-5777.2001. J Virol. 2001. PMID: 11390579 Free PMC article.
Carbohydrate-binding agents (CBAs) inhibit HIV-1 infection in human primary monocyte-derived macrophages (MDMs) and efficiently prevent MDM-directed viral capture and subsequent transmission to CD4+ T lymphocytes.
Pollicita M, Schols D, Aquaro S, Peumans WJ, Van Damme EJ, Perno CF, Balzarini J. Pollicita M, et al. Among authors: balzarini j. Virology. 2008 Jan 20;370(2):382-91. doi: 10.1016/j.virol.2007.08.033. Epub 2007 Oct 24. Virology. 2008. PMID: 17928023 Free article.
The phenylmethylthiazolylthiourea nonnucleoside reverse transcriptase (RT) inhibitor MSK-076 selects for a resistance mutation in the active site of human immunodeficiency virus type 2 RT.
Auwerx J, Stevens M, Van Rompay AR, Bird LE, Ren J, De Clercq E, Oberg B, Stammers DK, Karlsson A, Balzarini J. Auwerx J, et al. Among authors: balzarini j. J Virol. 2004 Jul;78(14):7427-37. doi: 10.1128/JVI.78.14.7427-7437.2004. J Virol. 2004. PMID: 15220416 Free PMC article.
1,243 results