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Page 1
Increasing Cu bioavailability inhibits Abeta oligomers and tau phosphorylation.
Crouch PJ, Hung LW, Adlard PA, Cortes M, Lal V, Filiz G, Perez KA, Nurjono M, Caragounis A, Du T, Laughton K, Volitakis I, Bush AI, Li QX, Masters CL, Cappai R, Cherny RA, Donnelly PS, White AR, Barnham KJ. Crouch PJ, et al. Proc Natl Acad Sci U S A. 2009 Jan 13;106(2):381-6. doi: 10.1073/pnas.0809057106. Epub 2009 Jan 2. Proc Natl Acad Sci U S A. 2009. PMID: 19122148 Free PMC article.
Degradation of the Alzheimer disease amyloid beta-peptide by metal-dependent up-regulation of metalloprotease activity.
White AR, Du T, Laughton KM, Volitakis I, Sharples RA, Xilinas ME, Hoke DE, Holsinger RM, Evin G, Cherny RA, Hill AF, Barnham KJ, Li QX, Bush AI, Masters CL. White AR, et al. Among authors: laughton km. J Biol Chem. 2006 Jun 30;281(26):17670-80. doi: 10.1074/jbc.M602487200. Epub 2006 Apr 28. J Biol Chem. 2006. PMID: 16648635 Free article.
Selective intracellular release of copper and zinc ions from bis(thiosemicarbazonato) complexes reduces levels of Alzheimer disease amyloid-beta peptide.
Donnelly PS, Caragounis A, Du T, Laughton KM, Volitakis I, Cherny RA, Sharples RA, Hill AF, Li QX, Masters CL, Barnham KJ, White AR. Donnelly PS, et al. Among authors: laughton km. J Biol Chem. 2008 Feb 22;283(8):4568-77. doi: 10.1074/jbc.M705957200. Epub 2007 Dec 17. J Biol Chem. 2008. PMID: 18086681 Free article.
Rapid restoration of cognition in Alzheimer's transgenic mice with 8-hydroxy quinoline analogs is associated with decreased interstitial Abeta.
Adlard PA, Cherny RA, Finkelstein DI, Gautier E, Robb E, Cortes M, Volitakis I, Liu X, Smith JP, Perez K, Laughton K, Li QX, Charman SA, Nicolazzo JA, Wilkins S, Deleva K, Lynch T, Kok G, Ritchie CW, Tanzi RE, Cappai R, Masters CL, Barnham KJ, Bush AI. Adlard PA, et al. Neuron. 2008 Jul 10;59(1):43-55. doi: 10.1016/j.neuron.2008.06.018. Neuron. 2008. PMID: 18614028 Free article.
Copper promotes the trafficking of the amyloid precursor protein.
Acevedo KM, Hung YH, Dalziel AH, Li QX, Laughton K, Wikhe K, Rembach A, Roberts B, Masters CL, Bush AI, Camakaris J. Acevedo KM, et al. Among authors: laughton k. J Biol Chem. 2011 Mar 11;286(10):8252-8262. doi: 10.1074/jbc.M110.128512. Epub 2010 Dec 22. J Biol Chem. 2011. PMID: 21177866 Free PMC article.
26 results