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Leptin directly activates SF1 neurons in the VMH, and this action by leptin is required for normal body-weight homeostasis.
Dhillon H, Zigman JM, Ye C, Lee CE, McGovern RA, Tang V, Kenny CD, Christiansen LM, White RD, Edelstein EA, Coppari R, Balthasar N, Cowley MA, Chua S Jr, Elmquist JK, Lowell BB. Dhillon H, et al. Among authors: coppari r. Neuron. 2006 Jan 19;49(2):191-203. doi: 10.1016/j.neuron.2005.12.021. Neuron. 2006. PMID: 16423694 Free article.
Mice lacking ghrelin receptors resist the development of diet-induced obesity.
Zigman JM, Nakano Y, Coppari R, Balthasar N, Marcus JN, Lee CE, Jones JE, Deysher AE, Waxman AR, White RD, Williams TD, Lachey JL, Seeley RJ, Lowell BB, Elmquist JK. Zigman JM, et al. Among authors: coppari r. J Clin Invest. 2005 Dec;115(12):3564-72. doi: 10.1172/JCI26002. J Clin Invest. 2005. PMID: 16322794 Free PMC article.
Collective and individual functions of leptin receptor modulated neurons controlling metabolism and ingestion.
van de Wall E, Leshan R, Xu AW, Balthasar N, Coppari R, Liu SM, Jo YH, MacKenzie RG, Allison DB, Dun NJ, Elmquist J, Lowell BB, Barsh GS, de Luca C, Myers MG Jr, Schwartz GJ, Chua SC Jr. van de Wall E, et al. Among authors: coppari r. Endocrinology. 2008 Apr;149(4):1773-85. doi: 10.1210/en.2007-1132. Epub 2007 Dec 27. Endocrinology. 2008. PMID: 18162515 Free PMC article.
62 results