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New pyrimido-indole compound CD-160130 preferentially inhibits the KV11.1B isoform and produces antileukemic effects without cardiotoxicity.
Gasparoli L, D'Amico M, Masselli M, Pillozzi S, Caves R, Khuwaileh R, Tiedke W, Mugridge K, Pratesi A, Mitcheson JS, Basso G, Becchetti A, Arcangeli A. Gasparoli L, et al. Among authors: pillozzi s. Mol Pharmacol. 2015 Feb;87(2):183-96. doi: 10.1124/mol.114.094920. Epub 2014 Nov 19. Mol Pharmacol. 2015. PMID: 25411366
HERG K+ channels activation during beta(1) integrin-mediated adhesion to fibronectin induces an up-regulation of alpha(v)beta(3) integrin in the preosteoclastic leukemia cell line FLG 29.1.
Hofmann G, Bernabei PA, Crociani O, Cherubini A, Guasti L, Pillozzi S, Lastraioli E, Polvani S, Bartolozzi B, Solazzo V, Gragnani L, Defilippi P, Rosati B, Wanke E, Olivotto M, Arcangeli A. Hofmann G, et al. Among authors: pillozzi s. J Biol Chem. 2001 Feb 16;276(7):4923-31. doi: 10.1074/jbc.M005682200. Epub 2000 Nov 15. J Biol Chem. 2001. PMID: 11080495 Free article.
New insights into the regulation of ion channels by integrins.
Becchetti A, Pillozzi S, Morini R, Nesti E, Arcangeli A. Becchetti A, et al. Among authors: pillozzi s. Int Rev Cell Mol Biol. 2010;279:135-90. doi: 10.1016/S1937-6448(10)79005-5. Epub 2010 Jan 29. Int Rev Cell Mol Biol. 2010. PMID: 20797679 Review.
107 results