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Page 1
C1'-cycloalkyl side chain pharmacophore in tetrahydrocannabinols.
Papahatjis DP, Nahmias VR, Nikas SP, Andreou T, Alapafuja SO, Tsotinis A, Guo J, Fan P, Makriyannis A. Papahatjis DP, et al. Among authors: nahmias vr. J Med Chem. 2007 Aug 23;50(17):4048-60. doi: 10.1021/jm070121a. Epub 2007 Aug 2. J Med Chem. 2007. PMID: 17672444
The application of 3D-QSAR studies for novel cannabinoid ligands substituted at the C1' position of the alkyl side chain on the structural requirements for binding to cannabinoid receptors CB1 and CB2.
Durdagi S, Kapou A, Kourouli T, Andreou T, Nikas SP, Nahmias VR, Papahatjis DP, Papadopoulos MG, Mavromoustakos T. Durdagi S, et al. Among authors: nahmias vr. J Med Chem. 2007 Jun 14;50(12):2875-85. doi: 10.1021/jm0610705. Epub 2007 May 24. J Med Chem. 2007. PMID: 17521177
Unnatural rigid scaffolds targeting the bacterial ribosome.
Katsoulis IA, Pyrkotis C, Papakyriakou A, Kythreoti G, Zografos AL, Mavridis I, Nahmias VR, Anastasopoulou P, Vourloumis D. Katsoulis IA, et al. Among authors: nahmias vr. Chembiochem. 2009 Aug 17;10(12):1969-72. doi: 10.1002/cbic.200900268. Chembiochem. 2009. PMID: 19585638 No abstract available.
Designed spiro-bicyclic analogues targeting the ribosomal decoding center.
Cottin T, Pyrkotis C, Stathakis CI, Mavridis I, Katsoulis IA, Anastasopoulou P, Kythreoti G, Zografos AL, Nahmias VR, Papakyriakou A, Vourloumis D. Cottin T, et al. Among authors: nahmias vr. Chembiochem. 2011 Jan 3;12(1):71-87. doi: 10.1002/cbic.201000591. Chembiochem. 2011. PMID: 21154494