Isobe K - Search Results

1

Suppression of viral replication by stress-inducible GADD34 protein via the mammalian serine/threonine protein kinase mTOR pathway.

Minami K, Tambe Y, Watanabe R, Isono T, Haneda M, Isobe K, Kobayashi T, Hino O, Okabe H, Chano T, Inoue H. Minami K, et al. Among authors: isobe k. J Virol. 2007 Oct;81(20):11106-15. doi: 10.1128/JVI.01063-07. Epub 2007 Aug 1. J Virol. 2007. PMID: 17670836 Free PMC article.

2

GADD34 inhibits mammalian target of rapamycin signaling via tuberous sclerosis complex and controls cell survival under bioenergetic stress.

Watanabe R, Tambe Y, Inoue H, Isono T, Haneda M, Isobe K, Kobayashi T, Hino O, Okabe H, Chano T. Watanabe R, et al. Among authors: isobe k. Int J Mol Med. 2007 Mar;19(3):475-83. Int J Mol Med. 2007. PMID: 17273797

3

GADD34 induces p21 expression and cellular senescence.

Minami K, Inoue H, Terashita T, Kawakami T, Watanabe R, Haneda M, Isobe K, Okabe H, Chano T. Minami K, et al. Among authors: isobe k. Oncol Rep. 2007 Jun;17(6):1481-5. Oncol Rep. 2007. PMID: 17487408

4

GADD34 induces p53 phosphorylation and p21/WAF1 transcription.

Yagi A, Hasegawa Y, Xiao H, Haneda M, Kojima E, Nishikimi A, Hasegawa T, Shimokata K, Isobe K. Yagi A, et al. Among authors: isobe k. J Cell Biochem. 2003 Dec 15;90(6):1242-9. doi: 10.1002/jcb.10711. J Cell Biochem. 2003. PMID: 14635196

5

Protein phosphatase 1, but not protein phosphatase 2A, dephosphorylates DNA-damaging stress-induced phospho-serine 15 of p53.

Haneda M, Kojima E, Nishikimi A, Hasegawa T, Nakashima I, Isobe K. Haneda M, et al. Among authors: isobe k. FEBS Lett. 2004 Jun 4;567(2-3):171-4. doi: 10.1016/j.febslet.2004.04.066. FEBS Lett. 2004. PMID: 15178317 Free article.

6

The function of GADD34 is a recovery from a shutoff of protein synthesis induced by ER stress: elucidation by GADD34-deficient mice.

Kojima E, Takeuchi A, Haneda M, Yagi A, Hasegawa T, Yamaki K, Takeda K, Akira S, Shimokata K, Isobe K. Kojima E, et al. Among authors: isobe k. FASEB J. 2003 Aug;17(11):1573-5. doi: 10.1096/fj.02-1184fje. Epub 2003 Jun 3. FASEB J. 2003. PMID: 12824288

7

Regulation of mouse GADD34 gene transcription after DNA damaging agent methylmethane sulfonate.

Haneda M, Xiao H, Hasegawa T, Kimura Y, Nakashima I, Isobe K. Haneda M, et al. Among authors: isobe k. Gene. 2004 Jul 7;336(1):139-46. doi: 10.1016/j.gene.2004.04.008. Gene. 2004. PMID: 15225883

8

Amyloid-beta peptides induce cell proliferation and macrophage colony-stimulating factor expression via the PI3-kinase/Akt pathway in cultured Ra2 microglial cells.

Ito S, Sawada M, Haneda M, Fujii S, Oh-Hashi K, Kiuchi K, Takahashi M, Isobe K. Ito S, et al. Among authors: isobe k. FEBS Lett. 2005 Mar 28;579(9):1995-2000. doi: 10.1016/j.febslet.2005.02.048. FEBS Lett. 2005. PMID: 15792809 Free article.

9

Cellular and systemic defense system against age-promoting stimuli.

Isobe K, Ito S, Haneda M, Ishida Y. Isobe K, et al. Nagoya J Med Sci. 2006 Jan;68(1-2):9-18. Nagoya J Med Sci. 2006. PMID: 16579171 Review.

10

Induction of matrix metalloproteinases (MMP3, MMP12 and MMP13) expression in the microglia by amyloid-beta stimulation via the PI3K/Akt pathway.

Ito S, Kimura K, Haneda M, Ishida Y, Sawada M, Isobe K. Ito S, et al. Among authors: isobe k. Exp Gerontol. 2007 Jun;42(6):532-7. doi: 10.1016/j.exger.2006.11.012. Epub 2007 Jan 2. Exp Gerontol. 2007. PMID: 17198748

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