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The Salmonella pathogenicity island (SPI)-2 and SPI-1 type III secretion systems allow Salmonella serovar typhimurium to trigger colitis via MyD88-dependent and MyD88-independent mechanisms.
Hapfelmeier S, Stecher B, Barthel M, Kremer M, Müller AJ, Heikenwalder M, Stallmach T, Hensel M, Pfeffer K, Akira S, Hardt WD. Hapfelmeier S, et al. Among authors: heikenwalder m. J Immunol. 2005 Feb 1;174(3):1675-85. doi: 10.4049/jimmunol.174.3.1675. J Immunol. 2005. PMID: 15661931
Expression of lymphotoxin beta governs immunity at two distinct levels.
Junt T, Tumanov AV, Harris N, Heikenwalder M, Zeller N, Kuprash DV, Aguzzi A, Ludewig B, Nedospasov SA, Zinkernagel RM. Junt T, et al. Among authors: heikenwalder m. Eur J Immunol. 2006 Aug;36(8):2061-75. doi: 10.1002/eji.200626255. Eur J Immunol. 2006. PMID: 16841297 Free article.
Immunoprivileged status of the liver is controlled by Toll-like receptor 3 signaling.
Lang KS, Georgiev P, Recher M, Navarini AA, Bergthaler A, Heikenwalder M, Harris NL, Junt T, Odermatt B, Clavien PA, Pircher H, Akira S, Hengartner H, Zinkernagel RM. Lang KS, et al. Among authors: heikenwalder m. J Clin Invest. 2006 Sep;116(9):2456-63. doi: 10.1172/JCI28349. J Clin Invest. 2006. PMID: 16955143 Free PMC article.
Overexpression of lymphotoxin in T cells induces fulminant thymic involution.
Heikenwalder M, Prinz M, Zeller N, Lang KS, Junt T, Rossi S, Tumanov A, Schmidt H, Priller J, Flatz L, Rülicke T, Macpherson AJ, Holländer GA, Nedospasov SA, Aguzzi A. Heikenwalder M, et al. Am J Pathol. 2008 Jun;172(6):1555-70. doi: 10.2353/ajpath.2008.070572. Epub 2008 May 15. Am J Pathol. 2008. PMID: 18483211 Free PMC article.
Intrahepatic myeloid-cell aggregates enable local proliferation of CD8(+) T cells and successful immunotherapy against chronic viral liver infection.
Huang LR, Wohlleber D, Reisinger F, Jenne CN, Cheng RL, Abdullah Z, Schildberg FA, Odenthal M, Dienes HP, van Rooijen N, Schmitt E, Garbi N, Croft M, Kurts C, Kubes P, Protzer U, Heikenwalder M, Knolle PA. Huang LR, et al. Among authors: heikenwalder m. Nat Immunol. 2013 Jun;14(6):574-83. doi: 10.1038/ni.2573. Epub 2013 Apr 14. Nat Immunol. 2013. PMID: 23584070
Tumor-necrosis factor impairs CD4(+) T cell-mediated immunological control in chronic viral infection.
Beyer M, Abdullah Z, Chemnitz JM, Maisel D, Sander J, Lehmann C, Thabet Y, Shinde PV, Schmidleithner L, Köhne M, Trebicka J, Schierwagen R, Hofmann A, Popov A, Lang KS, Oxenius A, Buch T, Kurts C, Heikenwalder M, Fätkenheuer G, Lang PA, Hartmann P, Knolle PA, Schultze JL. Beyer M, et al. Among authors: heikenwalder m. Nat Immunol. 2016 May;17(5):593-603. doi: 10.1038/ni.3399. Epub 2016 Mar 7. Nat Immunol. 2016. PMID: 26950238
346 results