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A biased ligand for OXE-R uncouples Gα and Gβγ signaling within a heterotrimer.
Blättermann S, Peters L, Ottersbach PA, Bock A, Konya V, Weaver CD, Gonzalez A, Schröder R, Tyagi R, Luschnig P, Gäb J, Hennen S, Ulven T, Pardo L, Mohr K, Gütschow M, Heinemann A, Kostenis E. Blättermann S, et al. Among authors: peters l. Nat Chem Biol. 2012 Jul;8(7):631-8. doi: 10.1038/nchembio.962. Epub 2012 May 27. Nat Chem Biol. 2012. PMID: 22634634
Decoding signaling and function of the orphan G protein-coupled receptor GPR17 with a small-molecule agonist.
Hennen S, Wang H, Peters L, Merten N, Simon K, Spinrath A, Blättermann S, Akkari R, Schrage R, Schröder R, Schulz D, Vermeiren C, Zimmermann K, Kehraus S, Drewke C, Pfeifer A, König GM, Mohr K, Gillard M, Müller CE, Lu QR, Gomeza J, Kostenis E. Hennen S, et al. Among authors: peters l. Sci Signal. 2013 Oct 22;6(298):ra93. doi: 10.1126/scisignal.2004350. Sci Signal. 2013. PMID: 24150254 Free PMC article.
The allosteric vestibule of a seven transmembrane helical receptor controls G-protein coupling.
Bock A, Merten N, Schrage R, Dallanoce C, Bätz J, Klöckner J, Schmitz J, Matera C, Simon K, Kebig A, Peters L, Müller A, Schrobang-Ley J, Tränkle C, Hoffmann C, De Amici M, Holzgrabe U, Kostenis E, Mohr K. Bock A, et al. Among authors: peters l. Nat Commun. 2012;3:1044. doi: 10.1038/ncomms2028. Nat Commun. 2012. PMID: 22948826 Free PMC article.
Repurposing HAMI3379 to Block GPR17 and Promote Rodent and Human Oligodendrocyte Differentiation.
Merten N, Fischer J, Simon K, Zhang L, Schröder R, Peters L, Letombe AG, Hennen S, Schrage R, Bödefeld T, Vermeiren C, Gillard M, Mohr K, Lu QR, Brüstle O, Gomeza J, Kostenis E. Merten N, et al. Among authors: peters l. Cell Chem Biol. 2018 Jun 21;25(6):775-786.e5. doi: 10.1016/j.chembiol.2018.03.012. Epub 2018 Apr 26. Cell Chem Biol. 2018. PMID: 29706593 Free PMC article.
Micellar Solvent Accessibility of Esterified Polyoxyethylene Chains as Crucial Element of Polysorbate Oxidation: A Density Functional Theory, Molecular Dynamics Simulation and Liquid Chromatography/Mass Spectrometry Investigation.
Weber J, Pedri L, Peters LP, Quoika PK, Dinu DF, Liedl KR, Tautermann CS, Diederichs T, Garidel P. Weber J, et al. Among authors: peters lp. Mol Pharm. 2025 Feb 3. doi: 10.1021/acs.molpharmaceut.4c01015. Online ahead of print. Mol Pharm. 2025. PMID: 39898560
Viremia Does Not Independently Predict Cardiovascular Disease in People With HIV: A RESPOND Cohort Study.
Elvstam O, Ryom L, Neesgaard B, Tau L, Günthard HF, Zangerle R, Vehreschild JJ, Wit F, Sönnerborg A, Kovari H, Abutidze A, Petoumenos K, Jaschinski N, Hosein S, Bogner J, Grabmeier-Pfistershammer K, Garges H, Rooney J, Young L, Law M, Kirk O; RESPOND Study Group. Elvstam O, et al. Open Forum Infect Dis. 2025 Jan 13;12(2):ofaf016. doi: 10.1093/ofid/ofaf016. eCollection 2025 Feb. Open Forum Infect Dis. 2025. PMID: 39896984 Free PMC article.
1,641 results