Bhat BG - Search Results

1

LPS-induced biomarkers in mice: a potential model for identifying insulin sensitizers.

Briscoe CP, Looper D, Tran P, Herrera J, McDonnell SR, Bhat BG. Briscoe CP, et al. Among authors: bhat bg. Biochem Biophys Res Commun. 2007 Sep 14;361(1):140-5. doi: 10.1016/j.bbrc.2007.06.164. Epub 2007 Jul 10. Biochem Biophys Res Commun. 2007. PMID: 17659259

2

Antisense inhibition of 11betahydroxysteroid dehydrogenase type 1 improves diabetes in a novel cortisone-induced diabetic KK mouse model.

Bhat BG, Younis H, Herrera J, Palacio K, Pascual B, Hur G, Jessen B, Ogilvie KM, Rejto PA. Bhat BG, et al. Biochem Biophys Res Commun. 2008 Jan 25;365(4):740-5. doi: 10.1016/j.bbrc.2007.11.032. Epub 2007 Nov 20. Biochem Biophys Res Commun. 2008. PMID: 18029262

3

Demonstration of proof of mechanism and pharmacokinetics and pharmacodynamic relationship with 4'-cyano-biphenyl-4-sulfonic acid (6-amino-pyridin-2-yl)-amide (PF-915275), an inhibitor of 11 -hydroxysteroid dehydrogenase type 1, in cynomolgus monkeys.

Bhat BG, Hosea N, Fanjul A, Herrera J, Chapman J, Thalacker F, Stewart PM, Rejto PA. Bhat BG, et al. J Pharmacol Exp Ther. 2008 Jan;324(1):299-305. doi: 10.1124/jpet.107.128280. Epub 2007 Oct 5. J Pharmacol Exp Ther. 2008. PMID: 17921190

4

Discovery of trifluoromethyl(pyrimidin-2-yl)azetidine-2-carboxamides as potent, orally bioavailable TGR5 (GPBAR1) agonists: structure-activity relationships, lead optimization, and chronic in vivo efficacy.

Phillips DP, Gao W, Yang Y, Zhang G, Lerario IK, Lau TL, Jiang J, Wang X, Nguyen DG, Bhat BG, Trotter C, Sullivan H, Welzel G, Landry J, Chen Y, Joseph SB, Li C, Gordon WP, Richmond W, Johnson K, Bretz A, Bursulaya B, Pan S, McNamara P, Seidel HM. Phillips DP, et al. Among authors: bhat bg. J Med Chem. 2014 Apr 24;57(8):3263-82. doi: 10.1021/jm401731q. Epub 2014 Apr 4. J Med Chem. 2014. PMID: 24666203

5

MicroRNAs 103 and 107 regulate insulin sensitivity.

Trajkovski M, Hausser J, Soutschek J, Bhat B, Akin A, Zavolan M, Heim MH, Stoffel M. Trajkovski M, et al. Nature. 2011 Jun 8;474(7353):649-53. doi: 10.1038/nature10112. Nature. 2011. PMID: 21654750

6

G-protein-coupled bile acid receptor 1 (GPBAR1, TGR5) agonists reduce the production of proinflammatory cytokines and stabilize the alternative macrophage phenotype.

Högenauer K, Arista L, Schmiedeberg N, Werner G, Jaksche H, Bouhelal R, Nguyen DG, Bhat BG, Raad L, Rauld C, Carballido JM. Högenauer K, et al. Among authors: bhat bg. J Med Chem. 2014 Dec 26;57(24):10343-54. doi: 10.1021/jm501052c. Epub 2014 Dec 9. J Med Chem. 2014. PMID: 25411721

7

Development of a high-throughput screening assay for stearoyl-CoA desaturase using rat liver microsomes, deuterium labeled stearoyl-CoA and mass spectrometry.

Soulard P, McLaughlin M, Stevens J, Connolly B, Coli R, Wang L, Moore J, Kuo MS, LaMarr WA, Ozbal CC, Bhat BG. Soulard P, et al. Among authors: bhat bg. Anal Chim Acta. 2008 Oct 3;627(1):105-11. doi: 10.1016/j.aca.2008.04.017. Epub 2008 Apr 15. Anal Chim Acta. 2008. PMID: 18790133

8

Development of a novel LC/MS method to quantitate cellular stearoyl-CoA desaturase activity.

Dillon R, Greig MJ, Bhat BG. Dillon R, et al. Among authors: bhat bg. Anal Chim Acta. 2008 Oct 3;627(1):99-104. doi: 10.1016/j.aca.2008.05.012. Epub 2008 May 15. Anal Chim Acta. 2008. PMID: 18790132

9

Inhibition of ileal bile acid transport and reduced atherosclerosis in apoE-/- mice by SC-435.

Bhat BG, Rapp SR, Beaudry JA, Napawan N, Butteiger DN, Hall KA, Null CL, Luo Y, Keller BT. Bhat BG, et al. J Lipid Res. 2003 Sep;44(9):1614-21. doi: 10.1194/jlr.M200469-JLR200. Epub 2003 Jun 16. J Lipid Res. 2003. PMID: 12810816 Free article.

10

Transcription profiling in rat liver in response to dietary docosahexaenoic acid implicates stearoyl-coenzyme a desaturase as a nutritional target for lipid lowering.

Kramer JA, LeDeaux J, Butteiger D, Young T, Crankshaw C, Harlow H, Kier L, Bhat BG. Kramer JA, et al. Among authors: bhat bg. J Nutr. 2003 Jan;133(1):57-66. doi: 10.1093/jn/133.1.57. J Nutr. 2003. PMID: 12514267

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