Rahme LG - Search Results

1

PqsA is required for the biosynthesis of 2,4-dihydroxyquinoline (DHQ), a newly identified metabolite produced by Pseudomonas aeruginosa and Burkholderia thailandensis.

Lépine F, Dekimpe V, Lesic B, Milot S, Lesimple A, Mamer OA, Rahme LG, Déziel E. Lépine F, et al. Among authors: rahme lg. Biol Chem. 2007 Aug;388(8):839-45. doi: 10.1515/BC.2007.100. Biol Chem. 2007. PMID: 17655503 Free PMC article.

2

A stable isotope dilution assay for the quantification of the Pseudomonas quinolone signal in Pseudomonas aeruginosa cultures.

Lépine F, Déziel E, Milot S, Rahme LG. Lépine F, et al. Among authors: rahme lg. Biochim Biophys Acta. 2003 Jun 20;1622(1):36-41. doi: 10.1016/s0304-4165(03)00103-x. Biochim Biophys Acta. 2003. PMID: 12829259

3

Electrospray/mass spectrometric identification and analysis of 4-hydroxy-2-alkylquinolines (HAQs) produced by Pseudomonas aeruginosa.

Lépine F, Milot S, Déziel E, He J, Rahme LG. Lépine F, et al. Among authors: rahme lg. J Am Soc Mass Spectrom. 2004 Jun;15(6):862-9. doi: 10.1016/j.jasms.2004.02.012. J Am Soc Mass Spectrom. 2004. PMID: 15144975 Free article.

4

The end of an old hypothesis: the pseudomonas signaling molecules 4-hydroxy-2-alkylquinolines derive from fatty acids, not 3-ketofatty acids.

Dulcey CE, Dekimpe V, Fauvelle DA, Milot S, Groleau MC, Doucet N, Rahme LG, Lépine F, Déziel E. Dulcey CE, et al. Among authors: rahme lg. Chem Biol. 2013 Dec 19;20(12):1481-91. doi: 10.1016/j.chembiol.2013.09.021. Epub 2013 Nov 14. Chem Biol. 2013. PMID: 24239007 Free PMC article.

5

Analysis of Pseudomonas aeruginosa 4-hydroxy-2-alkylquinolines (HAQs) reveals a role for 4-hydroxy-2-heptylquinoline in cell-to-cell communication.

Déziel E, Lépine F, Milot S, He J, Mindrinos MN, Tompkins RG, Rahme LG. Déziel E, et al. Among authors: rahme lg. Proc Natl Acad Sci U S A. 2004 Feb 3;101(5):1339-44. doi: 10.1073/pnas.0307694100. Epub 2004 Jan 22. Proc Natl Acad Sci U S A. 2004. PMID: 14739337 Free PMC article.

6

MvfR, a key Pseudomonas aeruginosa pathogenicity LTTR-class regulatory protein, has dual ligands.

Xiao G, Déziel E, He J, Lépine F, Lesic B, Castonguay MH, Milot S, Tampakaki AP, Stachel SE, Rahme LG. Xiao G, et al. Among authors: rahme lg. Mol Microbiol. 2006 Dec;62(6):1689-99. doi: 10.1111/j.1365-2958.2006.05462.x. Mol Microbiol. 2006. PMID: 17083468 Free article.

7

Polypharmacology Approaches against the Pseudomonas aeruginosa MvfR Regulon and Their Application in Blocking Virulence and Antibiotic Tolerance.

Maura D, Drees SL, Bandyopadhaya A, Kitao T, Negri M, Starkey M, Lesic B, Milot S, Déziel E, Zahler R, Pucci M, Felici A, Fetzner S, Lépine F, Rahme LG. Maura D, et al. Among authors: rahme lg. ACS Chem Biol. 2017 May 19;12(5):1435-1443. doi: 10.1021/acschembio.6b01139. Epub 2017 Apr 12. ACS Chem Biol. 2017. PMID: 28379691

8

Inhibitors of pathogen intercellular signals as selective anti-infective compounds.

Lesic B, Lépine F, Déziel E, Zhang J, Zhang Q, Padfield K, Castonguay MH, Milot S, Stachel S, Tzika AA, Tompkins RG, Rahme LG. Lesic B, et al. Among authors: rahme lg. PLoS Pathog. 2007 Sep 14;3(9):1229-39. doi: 10.1371/journal.ppat.0030126. PLoS Pathog. 2007. PMID: 17941706 Free PMC article.

9

Homeostatic interplay between bacterial cell-cell signaling and iron in virulence.

Hazan R, He J, Xiao G, Dekimpe V, Apidianakis Y, Lesic B, Astrakas C, Déziel E, Lépine F, Rahme LG. Hazan R, et al. Among authors: rahme lg. PLoS Pathog. 2010 Mar 12;6(3):e1000810. doi: 10.1371/journal.ppat.1000810. PLoS Pathog. 2010. PMID: 20300606 Free PMC article.

10

Tackling recalcitrant Pseudomonas aeruginosa infections in critical illness via anti-virulence monotherapy.

Singh VK, Almpani M, Maura D, Kitao T, Ferrari L, Fontana S, Bergamini G, Calcaterra E, Pignaffo C, Negri M, de Oliveira Pereira T, Skinner F, Gkikas M, Andreotti D, Felici A, Déziel E, Lépine F, Rahme LG. Singh VK, et al. Among authors: rahme lg. Nat Commun. 2022 Aug 30;13(1):5103. doi: 10.1038/s41467-022-32833-9. Nat Commun. 2022. PMID: 36042245 Free PMC article.

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