Wheeler KT - Search Results

1

Subcellular localization of sigma-2 receptors in breast cancer cells using two-photon and confocal microscopy.

Zeng C, Vangveravong S, Xu J, Chang KC, Hotchkiss RS, Wheeler KT, Shen D, Zhuang ZP, Kung HF, Mach RH. Zeng C, et al. Among authors: wheeler kt. Cancer Res. 2007 Jul 15;67(14):6708-16. doi: 10.1158/0008-5472.CAN-06-3803. Cancer Res. 2007. PMID: 17638881

2

Development of molecular probes for imaging sigma-2 receptors in vitro and in vivo.

Mach RH, Wheeler KT. Mach RH, et al. Among authors: wheeler kt. Cent Nerv Syst Agents Med Chem. 2009 Sep;9(3):230-45. doi: 10.2174/1871524910909030230. Cent Nerv Syst Agents Med Chem. 2009. PMID: 20021357 Free PMC article. Review.

3

Identification of the PGRMC1 protein complex as the putative sigma-2 receptor binding site.

Xu J, Zeng C, Chu W, Pan F, Rothfuss JM, Zhang F, Tu Z, Zhou D, Zeng D, Vangveravong S, Johnston F, Spitzer D, Chang KC, Hotchkiss RS, Hawkins WG, Wheeler KT, Mach RH. Xu J, et al. Among authors: wheeler kt. Nat Commun. 2011 Jul 5;2:380. doi: 10.1038/ncomms1386. Nat Commun. 2011. PMID: 21730960 Free PMC article.

4

Sigma 2 receptors as potential biomarkers of proliferation in breast cancer.

Mach RH, Smith CR, al-Nabulsi I, Whirrett BR, Childers SR, Wheeler KT. Mach RH, et al. Among authors: wheeler kt. Cancer Res. 1997 Jan 1;57(1):156-61. Cancer Res. 1997. PMID: 8988058

5

Carbon-11 labeled sigma2 receptor ligands for imaging breast cancer.

Tu Z, Dence CS, Ponde DE, Jones L, Wheeler KT, Welch MJ, Mach RH. Tu Z, et al. Among authors: wheeler kt. Nucl Med Biol. 2005 Jul;32(5):423-30. doi: 10.1016/j.nucmedbio.2005.03.008. Nucl Med Biol. 2005. PMID: 15982571

6

[3H]N-[4-(3,4-dihydro-6,7-dimethoxyisoquinolin-2(1H)-yl)butyl]-2-methoxy-5-methylbenzamide: a novel sigma-2 receptor probe.

Xu J, Tu Z, Jones LA, Vangveravong S, Wheeler KT, Mach RH. Xu J, et al. Among authors: wheeler kt. Eur J Pharmacol. 2005 Nov 21;525(1-3):8-17. doi: 10.1016/j.ejphar.2005.09.063. Epub 2005 Nov 10. Eur J Pharmacol. 2005. PMID: 16289030

7

Fluorine-18-labeled benzamide analogues for imaging the sigma2 receptor status of solid tumors with positron emission tomography.

Tu Z, Xu J, Jones LA, Li S, Dumstorff C, Vangveravong S, Chen DL, Wheeler KT, Welch MJ, Mach RH. Tu Z, et al. Among authors: wheeler kt. J Med Chem. 2007 Jul 12;50(14):3194-204. doi: 10.1021/jm0614883. Epub 2007 Jun 19. J Med Chem. 2007. PMID: 17579383

8

New N-substituted 9-azabicyclo[3.3.1]nonan-3alpha-yl phenylcarbamate analogs as sigma2 receptor ligands: synthesis, in vitro characterization, and evaluation as PET imaging and chemosensitization agents.

Chu W, Xu J, Zhou D, Zhang F, Jones LA, Wheeler KT, Mach RH. Chu W, et al. Among authors: wheeler kt. Bioorg Med Chem. 2009 Feb 1;17(3):1222-31. doi: 10.1016/j.bmc.2008.12.025. Epub 2008 Dec 24. Bioorg Med Chem. 2009. PMID: 19119012 Free PMC article.

9

Sigma-2 receptors as a biomarker of proliferation in solid tumours.

Wheeler KT, Wang LM, Wallen CA, Childers SR, Cline JM, Keng PC, Mach RH. Wheeler KT, et al. Br J Cancer. 2000 Mar;82(6):1223-32. doi: 10.1054/bjoc.1999.1067. Br J Cancer. 2000. PMID: 10735510 Free PMC article.

10

Quantitative receptor-based imaging of tumor proliferation with the sigma-2 ligand [(18)F]ISO-1.

Shoghi KI, Xu J, Su Y, He J, Rowland D, Yan Y, Garbow JR, Tu Z, Jones LA, Higashikubo R, Wheeler KT, Lubet RA, Mach RH, You M. Shoghi KI, et al. Among authors: wheeler kt. PLoS One. 2013 Sep 20;8(9):e74188. doi: 10.1371/journal.pone.0074188. eCollection 2013. PLoS One. 2013. PMID: 24073202 Free PMC article.

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