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Cotransplantation of ex vivo expanded mesenchymal stem cells accelerates lymphocyte recovery and may reduce the risk of graft failure in haploidentical hematopoietic stem-cell transplantation.
Ball LM, Bernardo ME, Roelofs H, Lankester A, Cometa A, Egeler RM, Locatelli F, Fibbe WE. Ball LM, et al. Among authors: cometa a. Blood. 2007 Oct 1;110(7):2764-7. doi: 10.1182/blood-2007-04-087056. Epub 2007 Jul 16. Blood. 2007. PMID: 17638847 Free article. Clinical Trial.
Co-infusion of ex vivo-expanded, parental MSCs prevents life-threatening acute GVHD, but does not reduce the risk of graft failure in pediatric patients undergoing allogeneic umbilical cord blood transplantation.
Bernardo ME, Ball LM, Cometa AM, Roelofs H, Zecca M, Avanzini MA, Bertaina A, Vinti L, Lankester A, Maccario R, Ringden O, Le Blanc K, Egeler RM, Fibbe WE, Locatelli F. Bernardo ME, et al. Among authors: cometa am. Bone Marrow Transplant. 2011 Feb;46(2):200-7. doi: 10.1038/bmt.2010.87. Epub 2010 Apr 19. Bone Marrow Transplant. 2011. PMID: 20400983
Ex vivo expansion of mesenchymal stromal cells.
Bernardo ME, Cometa AM, Pagliara D, Vinti L, Rossi F, Cristantielli R, Palumbo G, Locatelli F. Bernardo ME, et al. Best Pract Res Clin Haematol. 2011 Mar;24(1):73-81. doi: 10.1016/j.beha.2010.11.002. Epub 2011 Feb 23. Best Pract Res Clin Haematol. 2011. PMID: 21396595 Review.
Generation of mesenchymal stromal cells in the presence of platelet lysate: a phenotypic and functional comparison of umbilical cord blood- and bone marrow-derived progenitors.
Avanzini MA, Bernardo ME, Cometa AM, Perotti C, Zaffaroni N, Novara F, Visai L, Moretta A, Del Fante C, Villa R, Ball LM, Fibbe WE, Maccario R, Locatelli F. Avanzini MA, et al. Among authors: cometa am. Haematologica. 2009 Dec;94(12):1649-60. doi: 10.3324/haematol.2009.006171. Epub 2009 Sep 22. Haematologica. 2009. PMID: 19773264 Free PMC article.
Human bone marrow derived mesenchymal stem cells do not undergo transformation after long-term in vitro culture and do not exhibit telomere maintenance mechanisms.
Bernardo ME, Zaffaroni N, Novara F, Cometa AM, Avanzini MA, Moretta A, Montagna D, Maccario R, Villa R, Daidone MG, Zuffardi O, Locatelli F. Bernardo ME, et al. Among authors: cometa am. Cancer Res. 2007 Oct 1;67(19):9142-9. doi: 10.1158/0008-5472.CAN-06-4690. Cancer Res. 2007. PMID: 17909019
Human mesenchymal stem cells and cyclosporin a exert a synergistic suppressive effect on in vitro activation of alloantigen-specific cytotoxic lymphocytes.
Maccario R, Moretta A, Cometa A, Montagna D, Comoli P, Locatelli F, Podestà M, Frassoni F. Maccario R, et al. Among authors: cometa a. Biol Blood Marrow Transplant. 2005 Dec;11(12):1031-2. doi: 10.1016/j.bbmt.2005.08.039. Biol Blood Marrow Transplant. 2005. PMID: 16338626 Free article. No abstract available.
35 results