Thomas PM - Search Results

1

Unusual transformations in the biosynthesis of the antibiotic phosphinothricin tripeptide.

Blodgett JA, Thomas PM, Li G, Velasquez JE, van der Donk WA, Kelleher NL, Metcalf WW. Blodgett JA, et al. Among authors: thomas pm. Nat Chem Biol. 2007 Aug;3(8):480-5. doi: 10.1038/nchembio.2007.9. Epub 2007 Jul 15. Nat Chem Biol. 2007. PMID: 17632514 Free PMC article.

2

Discovery and in vitro biosynthesis of haloduracin, a two-component lantibiotic.

McClerren AL, Cooper LE, Quan C, Thomas PM, Kelleher NL, van der Donk WA. McClerren AL, et al. Among authors: thomas pm. Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17243-8. doi: 10.1073/pnas.0606088103. Epub 2006 Nov 3. Proc Natl Acad Sci U S A. 2006. PMID: 17085596 Free PMC article.

3

Heterologous production of fosfomycin and identification of the minimal biosynthetic gene cluster.

Woodyer RD, Shao Z, Thomas PM, Kelleher NL, Blodgett JA, Metcalf WW, van der Donk WA, Zhao H. Woodyer RD, et al. Among authors: thomas pm. Chem Biol. 2006 Nov;13(11):1171-82. doi: 10.1016/j.chembiol.2006.09.007. Chem Biol. 2006. PMID: 17113999

4

Top-down proteomics on a chromatographic time scale using linear ion trap fourier transform hybrid mass spectrometers.

Parks BA, Jiang L, Thomas PM, Wenger CD, Roth MJ, Boyne MT 2nd, Burke PV, Kwast KE, Kelleher NL. Parks BA, et al. Among authors: thomas pm. Anal Chem. 2007 Nov 1;79(21):7984-91. doi: 10.1021/ac070553t. Epub 2007 Oct 5. Anal Chem. 2007. PMID: 17915963 Free PMC article.

5

Reassignment of the structure of the antibiotic A53868 reveals an unusual amino dehydrophosphonic acid.

Whitteck JT, Ni W, Griffin BM, Eliot AC, Thomas PM, Kelleher NL, Metcalf WW, van der Donk WA. Whitteck JT, et al. Among authors: thomas pm. Angew Chem Int Ed Engl. 2007;46(47):9089-92. doi: 10.1002/anie.200703810. Angew Chem Int Ed Engl. 2007. PMID: 17990255 No abstract available.

6

Deconstruction of iterative multidomain polyketide synthase function.

Crawford JM, Thomas PM, Scheerer JR, Vagstad AL, Kelleher NL, Townsend CA. Crawford JM, et al. Among authors: thomas pm. Science. 2008 Apr 11;320(5873):243-6. doi: 10.1126/science.1154711. Science. 2008. PMID: 18403714 Free PMC article.

7

Gatekeeping versus promiscuity in the early stages of the andrimid biosynthetic assembly line.

Magarvey NA, Fortin PD, Thomas PM, Kelleher NL, Walsh CT. Magarvey NA, et al. Among authors: thomas pm. ACS Chem Biol. 2008 Sep 19;3(9):542-54. doi: 10.1021/cb800085g. Epub 2008 Jul 25. ACS Chem Biol. 2008. PMID: 18652473 Free PMC article.

8

Cloning, expression, and biochemical characterization of Streptomyces rubellomurinus genes required for biosynthesis of antimalarial compound FR900098.

Eliot AC, Griffin BM, Thomas PM, Johannes TW, Kelleher NL, Zhao H, Metcalf WW. Eliot AC, et al. Among authors: thomas pm. Chem Biol. 2008 Aug 25;15(8):765-70. doi: 10.1016/j.chembiol.2008.07.010. Chem Biol. 2008. PMID: 18721747 Free PMC article.

9

In vitro biosynthesis of unnatural enterocin and wailupemycin polyketides.

Kalaitzis JA, Cheng Q, Thomas PM, Kelleher NL, Moore BS. Kalaitzis JA, et al. Among authors: thomas pm. J Nat Prod. 2009 Mar 27;72(3):469-72. doi: 10.1021/np800598t. J Nat Prod. 2009. PMID: 19215142 Free PMC article.

10

A proteomics approach to discovering natural products and their biosynthetic pathways.

Bumpus SB, Evans BS, Thomas PM, Ntai I, Kelleher NL. Bumpus SB, et al. Among authors: thomas pm. Nat Biotechnol. 2009 Oct;27(10):951-6. doi: 10.1038/nbt.1565. Epub 2009 Sep 20. Nat Biotechnol. 2009. PMID: 19767731 Free PMC article.

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