Goedegebuure PS - Search Results

1

Selective sigma-2 ligands preferentially bind to pancreatic adenocarcinomas: applications in diagnostic imaging and therapy.

Kashiwagi H, McDunn JE, Simon PO Jr, Goedegebuure PS, Xu J, Jones L, Chang K, Johnston F, Trinkaus K, Hotchkiss RS, Mach RH, Hawkins WG. Kashiwagi H, et al. Among authors: goedegebuure ps. Mol Cancer. 2007 Jul 15;6:48. doi: 10.1186/1476-4598-6-48. Mol Cancer. 2007. PMID: 17631687 Free PMC article.

2

The novel sigma-2 receptor ligand SW43 stabilizes pancreas cancer progression in combination with gemcitabine.

Hornick JR, Xu J, Vangveravong S, Tu Z, Mitchem JB, Spitzer D, Goedegebuure P, Mach RH, Hawkins WG. Hornick JR, et al. Mol Cancer. 2010 Nov 22;9:298. doi: 10.1186/1476-4598-9-298. Mol Cancer. 2010. PMID: 21092190 Free PMC article.

3

Use of multifunctional sigma-2 receptor ligand conjugates to trigger cancer-selective cell death signaling.

Spitzer D, Simon PO Jr, Kashiwagi H, Xu J, Zeng C, Vangveravong S, Zhou D, Chang K, McDunn JE, Hornick JR, Goedegebuure P, Hotchkiss RS, Mach RH, Hawkins WG. Spitzer D, et al. Cancer Res. 2012 Jan 1;72(1):201-9. doi: 10.1158/0008-5472.CAN-11-1354. Epub 2011 Nov 7. Cancer Res. 2012. PMID: 22065721 Free PMC article.

4

Lysosomal membrane permeabilization is an early event in Sigma-2 receptor ligand mediated cell death in pancreatic cancer.

Hornick JR, Vangveravong S, Spitzer D, Abate C, Berardi F, Goedegebuure P, Mach RH, Hawkins WG. Hornick JR, et al. J Exp Clin Cancer Res. 2012 May 2;31(1):41. doi: 10.1186/1756-9966-31-41. J Exp Clin Cancer Res. 2012. PMID: 22551149 Free PMC article.

5

Therapeutic targeting of pancreatic cancer utilizing sigma-2 ligands.

Hornick JR, Spitzer D, Goedegebuure P, Mach RH, Hawkins WG. Hornick JR, et al. Surgery. 2012 Sep;152(3 Suppl 1):S152-6. doi: 10.1016/j.surg.2012.05.014. Epub 2012 Jul 3. Surgery. 2012. PMID: 22763259 Free PMC article. Review.

6

Targeted pancreatic cancer therapy with the small molecule drug conjugate SW IV-134.

Hashim YM, Spitzer D, Vangveravong S, Hornick MC, Garg G, Hornick JR, Goedegebuure P, Mach RH, Hawkins WG. Hashim YM, et al. Mol Oncol. 2014 Jul;8(5):956-67. doi: 10.1016/j.molonc.2014.03.005. Epub 2014 Mar 26. Mol Oncol. 2014. PMID: 24731702 Free PMC article.

7

TAT-Bim induces extensive apoptosis in cancer cells.

Kashiwagi H, McDunn JE, Goedegebuure PS, Gaffney MC, Chang K, Trinkaus K, Piwnica-Worms D, Hotchkiss RS, Hawkins WG. Kashiwagi H, et al. Among authors: goedegebuure ps. Ann Surg Oncol. 2007 May;14(5):1763-71. doi: 10.1245/s10434-006-9298-z. Epub 2007 Jan 6. Ann Surg Oncol. 2007. PMID: 17206479

8

Sigma-2 receptor ligands potentiate conventional chemotherapies and improve survival in models of pancreatic adenocarcinoma.

Kashiwagi H, McDunn JE, Simon PO Jr, Goedegebuure PS, Vangveravong S, Chang K, Hotchkiss RS, Mach RH, Hawkins WG. Kashiwagi H, et al. Among authors: goedegebuure ps. J Transl Med. 2009 Mar 26;7:24. doi: 10.1186/1479-5876-7-24. J Transl Med. 2009. PMID: 19323815 Free PMC article.

9

Targeting AKT with the proapoptotic peptide, TAT-CTMP: a novel strategy for the treatment of human pancreatic adenocarcinoma.

Simon PO Jr, McDunn JE, Kashiwagi H, Chang K, Goedegebuure PS, Hotchkiss RS, Hawkins WG. Simon PO Jr, et al. Among authors: goedegebuure ps. Int J Cancer. 2009 Aug 15;125(4):942-51. doi: 10.1002/ijc.24424. Int J Cancer. 2009. PMID: 19405118 Free PMC article.

10

A genetically encoded multifunctional TRAIL trimer facilitates cell-specific targeting and tumor cell killing.

Spitzer D, McDunn JE, Plambeck-Suess S, Goedegebuure PS, Hotchkiss RS, Hawkins WG. Spitzer D, et al. Among authors: goedegebuure ps. Mol Cancer Ther. 2010 Jul;9(7):2142-51. doi: 10.1158/1535-7163.MCT-10-0225. Epub 2010 Jun 22. Mol Cancer Ther. 2010. PMID: 20571073 Free PMC article.

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