Moretti L - Search Results

1

Autophagy signaling in cancer and its potential as novel target to improve anticancer therapy.

Moretti L, Yang ES, Kim KW, Lu B. Moretti L, et al. Drug Resist Updat. 2007 Aug-Oct;10(4-5):135-43. doi: 10.1016/j.drup.2007.05.001. Epub 2007 Jul 12. Drug Resist Updat. 2007. PMID: 17627865 Review.

2

Crosstalk between Bak/Bax and mTOR signaling regulates radiation-induced autophagy.

Moretti L, Attia A, Kim KW, Lu B. Moretti L, et al. Autophagy. 2007 Mar-Apr;3(2):142-4. doi: 10.4161/auto.3607. Epub 2007 Mar 20. Autophagy. 2007. PMID: 17204849

3

The role of mTOR inhibition in augmenting radiation induced autophagy.

Jaboin JJ, Shinohara ET, Moretti L, Yang ES, Kaminski JM, Lu B. Jaboin JJ, et al. Among authors: moretti l. Technol Cancer Res Treat. 2007 Oct;6(5):443-7. doi: 10.1177/153303460700600510. Technol Cancer Res Treat. 2007. PMID: 17877432 Free article. Review.

4

Autophagy upregulation by inhibitors of caspase-3 and mTOR enhances radiotherapy in a mouse model of lung cancer.

Kim KW, Hwang M, Moretti L, Jaboin JJ, Cha YI, Lu B. Kim KW, et al. Among authors: moretti l. Autophagy. 2008 Jul;4(5):659-68. doi: 10.4161/auto.6058. Epub 2008 Apr 7. Autophagy. 2008. PMID: 18424912 Free PMC article.

5

M867, a novel selective inhibitor of caspase-3 enhances cell death and extends tumor growth delay in irradiated lung cancer models.

Kim KW, Moretti L, Lu B. Kim KW, et al. Among authors: moretti l. PLoS One. 2008 May 28;3(5):e2275. doi: 10.1371/journal.pone.0002275. PLoS One. 2008. PMID: 18509530 Free PMC article.

6

HSP90 inhibitors: multi-targeted antitumor effects and novel combinatorial therapeutic approaches in cancer therapy.

Hwang M, Moretti L, Lu B. Hwang M, et al. Among authors: moretti l. Curr Med Chem. 2009;16(24):3081-92. doi: 10.2174/092986709788802999. Curr Med Chem. 2009. PMID: 19689285 Review.

7

Combined Bcl-2/mammalian target of rapamycin inhibition leads to enhanced radiosensitization via induction of apoptosis and autophagy in non-small cell lung tumor xenograft model.

Kim KW, Moretti L, Mitchell LR, Jung DK, Lu B. Kim KW, et al. Among authors: moretti l. Clin Cancer Res. 2009 Oct 1;15(19):6096-105. doi: 10.1158/1078-0432.CCR-09-0589. Epub 2009 Sep 22. Clin Cancer Res. 2009. PMID: 19773376 Free PMC article.

8

Progress in the unraveling of the endoplasmic reticulum stress/autophagy pathway and cancer: implications for future therapeutic approaches.

Schleicher SM, Moretti L, Varki V, Lu B. Schleicher SM, et al. Among authors: moretti l. Drug Resist Updat. 2010 Jun;13(3):79-86. doi: 10.1016/j.drup.2010.04.002. Epub 2010 May 15. Drug Resist Updat. 2010. PMID: 20471904 Review.

9

The mTOR signaling network: insights from its role during embryonic development.

Hwang M, Perez CA, Moretti L, Lu B. Hwang M, et al. Among authors: moretti l. Curr Med Chem. 2008;15(12):1192-208. doi: 10.2174/092986708784310459. Curr Med Chem. 2008. PMID: 18473813 Review.

10

Endoplasmic reticulum stress mediates radiation-induced autophagy by perk-eIF2alpha in caspase-3/7-deficient cells.

Kim KW, Moretti L, Mitchell LR, Jung DK, Lu B. Kim KW, et al. Among authors: moretti l. Oncogene. 2010 Jun 3;29(22):3241-51. doi: 10.1038/onc.2010.74. Epub 2010 Mar 29. Oncogene. 2010. PMID: 20348950 Free PMC article.

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