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Page 1
Modified 5'-trityl nucleosides as inhibitors of Plasmodium falciparum dUTPase.
Ruda GF, Nguyen C, Ziemkowski P, Felczak K, Kasinathan G, Musso-Buendia A, Sund C, Zhou XX, Kaiser M, Ruiz-Pérez LM, Brun R, Kulikowski T, Johansson NG, González-Pacanowska D, Gilbert IH. Ruda GF, et al. ChemMedChem. 2011 Feb 7;6(2):309-20. doi: 10.1002/cmdc.201000445. Epub 2011 Jan 18. ChemMedChem. 2011. PMID: 21246738
Acyclic nucleoside analogues as inhibitors of Plasmodium falciparum dUTPase.
Nguyen C, Ruda GF, Schipani A, Kasinathan G, Leal I, Musso-Buendia A, Kaiser M, Brun R, Ruiz-Pérez LM, Sahlberg BL, Johansson NG, Gonzalez-Pacanowska D, Gilbert IH. Nguyen C, et al. Among authors: ruda gf. J Med Chem. 2006 Jul 13;49(14):4183-95. doi: 10.1021/jm060126s. J Med Chem. 2006. PMID: 16821778
N-myristoyltransferase is a cell wall target in Aspergillus fumigatus.
Fang W, Robinson DA, Raimi OG, Blair DE, Harrison JR, Lockhart DE, Torrie LS, Ruda GF, Wyatt PG, Gilbert IH, van Aalten DM. Fang W, et al. Among authors: ruda gf. ACS Chem Biol. 2015 Jun 19;10(6):1425-34. doi: 10.1021/cb5008647. Epub 2015 Feb 27. ACS Chem Biol. 2015. PMID: 25706802 Free PMC article.
Automated design of ligands to polypharmacological profiles.
Besnard J, Ruda GF, Setola V, Abecassis K, Rodriguiz RM, Huang XP, Norval S, Sassano MF, Shin AI, Webster LA, Simeons FR, Stojanovski L, Prat A, Seidah NG, Constam DB, Bickerton GR, Read KD, Wetsel WC, Gilbert IH, Roth BL, Hopkins AL. Besnard J, et al. Among authors: ruda gf. Nature. 2012 Dec 13;492(7428):215-20. doi: 10.1038/nature11691. Nature. 2012. PMID: 23235874 Free PMC article.
24 results