Phylip LH - Search Results

1

N-terminal extension of the yeast IA3 aspartic proteinase inhibitor relaxes the strict intrinsic selectivity.

Winterburn TJ, Phylip LH, Bur D, Wyatt DM, Berry C, Kay J. Winterburn TJ, et al. Among authors: phylip lh. FEBS J. 2007 Jul;274(14):3685-3694. doi: 10.1111/j.1742-4658.2007.05901.x. Epub 2007 Jul 2. FEBS J. 2007. PMID: 17608726 Free article.

2

Adaptation of the behaviour of an aspartic proteinase inhibitor by relocation of a lysine residue by one helical turn.

Winterburn TJ, Wyatt DM, Phylip LH, Berry C, Bur D, Kay J. Winterburn TJ, et al. Among authors: phylip lh. Biol Chem. 2006 Aug;387(8):1139-42. doi: 10.1515/BC.2006.140. Biol Chem. 2006. PMID: 16895485

3

Key features determining the specificity of aspartic proteinase inhibition by the helix-forming IA3 polypeptide.

Winterburn TJ, Wyatt DM, Phylip LH, Bur D, Harrison RJ, Berry C, Kay J. Winterburn TJ, et al. Among authors: phylip lh. J Biol Chem. 2007 Mar 2;282(9):6508-16. doi: 10.1074/jbc.M610503200. Epub 2006 Dec 4. J Biol Chem. 2007. PMID: 17145748 Free article.

4

High level expression and characterisation of Plasmepsin II, an aspartic proteinase from Plasmodium falciparum.

Hill J, Tyas L, Phylip LH, Kay J, Dunn BM, Berry C. Hill J, et al. Among authors: phylip lh. FEBS Lett. 1994 Sep 26;352(2):155-8. doi: 10.1016/0014-5793(94)00940-6. FEBS Lett. 1994. PMID: 7925966 Free article.

5

The potency and specificity of the interaction between the IA3 inhibitor and its target aspartic proteinase from Saccharomyces cerevisiae.

Phylip LH, Lees WE, Brownsey BG, Bur D, Dunn BM, Winther JR, Gustchina A, Li M, Copeland T, Wlodawer A, Kay J. Phylip LH, et al. J Biol Chem. 2001 Jan 19;276(3):2023-30. doi: 10.1074/jbc.M008520200. Epub 2000 Oct 19. J Biol Chem. 2001. PMID: 11042188 Free article.

6

Aspartic proteinase inhibitors from tomato and potato are more potent against yeast proteinase A than cathepsin D.

Cater SA, Lees WE, Hill J, Brzin J, Kay J, Phylip LH. Cater SA, et al. Among authors: phylip lh. Biochim Biophys Acta. 2002 Apr 1;1596(1):76-82. doi: 10.1016/s0167-4838(02)00206-6. Biochim Biophys Acta. 2002. PMID: 11983423

7

Intrinsic activity of precursor forms of HIV-1 proteinase.

Phylip LH, Mills JS, Parten BF, Dunn BM, Kay J. Phylip LH, et al. FEBS Lett. 1992 Dec 21;314(3):449-54. doi: 10.1016/0014-5793(92)81524-p. FEBS Lett. 1992. PMID: 1468583 Free article.

8

An aspartic proteinase gene family in the filamentous fungus Botrytis cinerea contains members with novel features.

Ten Have A, Dekkers E, Kay J, Phylip LH, van Kan JAL. Ten Have A, et al. Among authors: phylip lh. Microbiology (Reading). 2004 Jul;150(Pt 7):2475-2489. doi: 10.1099/mic.0.27058-0. Microbiology (Reading). 2004. PMID: 15256589 Free article.

9

Mutating P2 and P1 residues at cleavage junctions in the HIV-1 pol polyprotein. Effects on hydrolysis by HIV-1 proteinase.

Jupp RA, Phylip LH, Mills JS, Le Grice SF, Kay J. Jupp RA, et al. Among authors: phylip lh. FEBS Lett. 1991 Jun 3;283(2):180-4. doi: 10.1016/0014-5793(91)80583-o. FEBS Lett. 1991. PMID: 2044756 Free article.

10

Escape mutants of HIV-1 proteinase: enzymic efficiency and susceptibility to inhibition.

Wilson SI, Phylip LH, Mills JS, Gulnik SV, Erickson JW, Dunn BM, Kay J. Wilson SI, et al. Among authors: phylip lh. Biochim Biophys Acta. 1997 Apr 25;1339(1):113-25. doi: 10.1016/s0167-4838(96)00224-5. Biochim Biophys Acta. 1997. PMID: 9165106

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