Henske EP - Search Results

1

HEF1-dependent Aurora A activation induces disassembly of the primary cilium.

Pugacheva EN, Jablonski SA, Hartman TR, Henske EP, Golemis EA. Pugacheva EN, et al. Among authors: henske ep. Cell. 2007 Jun 29;129(7):1351-63. doi: 10.1016/j.cell.2007.04.035. Cell. 2007. PMID: 17604723 Free PMC article.

2

The tuberous sclerosis proteins regulate formation of the primary cilium via a rapamycin-insensitive and polycystin 1-independent pathway.

Hartman TR, Liu D, Zilfou JT, Robb V, Morrison T, Watnick T, Henske EP. Hartman TR, et al. Among authors: henske ep. Hum Mol Genet. 2009 Jan 1;18(1):151-63. doi: 10.1093/hmg/ddn325. Epub 2008 Oct 9. Hum Mol Genet. 2009. PMID: 18845692 Free PMC article.

3

The Birt-Hogg-Dube and tuberous sclerosis complex homologs have opposing roles in amino acid homeostasis in Schizosaccharomyces pombe.

van Slegtenhorst M, Khabibullin D, Hartman TR, Nicolas E, Kruger WD, Henske EP. van Slegtenhorst M, et al. Among authors: henske ep. J Biol Chem. 2007 Aug 24;282(34):24583-90. doi: 10.1074/jbc.M700857200. Epub 2007 Jun 7. J Biol Chem. 2007. PMID: 17556368 Free article.

4

The role of the Birt-Hogg-Dubé protein in mTOR activation and renal tumorigenesis.

Hartman TR, Nicolas E, Klein-Szanto A, Al-Saleem T, Cash TP, Simon MC, Henske EP. Hartman TR, et al. Among authors: henske ep. Oncogene. 2009 Apr 2;28(13):1594-604. doi: 10.1038/onc.2009.14. Epub 2009 Feb 23. Oncogene. 2009. PMID: 19234517 Free PMC article.

5

Loss of the Birt-Hogg-Dubé tumor suppressor results in apoptotic resistance due to aberrant TGFβ-mediated transcription.

Cash TP, Gruber JJ, Hartman TR, Henske EP, Simon MC. Cash TP, et al. Among authors: henske ep. Oncogene. 2011 Jun 2;30(22):2534-46. doi: 10.1038/onc.2010.628. Epub 2011 Jan 24. Oncogene. 2011. PMID: 21258407 Free PMC article.

6

The evolutionarily conserved TSC/Rheb pathway activates Notch in tuberous sclerosis complex and Drosophila external sensory organ development.

Karbowniczek M, Zitserman D, Khabibullin D, Hartman T, Yu J, Morrison T, Nicolas E, Squillace R, Roegiers F, Henske EP. Karbowniczek M, et al. Among authors: henske ep. J Clin Invest. 2010 Jan;120(1):93-102. doi: 10.1172/JCI40221. Epub 2009 Dec 28. J Clin Invest. 2010. PMID: 20038815 Free PMC article.

7

The p53 target Plk2 interacts with TSC proteins impacting mTOR signaling, tumor growth and chemosensitivity under hypoxic conditions.

Matthew EM, Hart LS, Astrinidis A, Navaraj A, Dolloff NG, Dicker DT, Henske EP, El-Deiry WS. Matthew EM, et al. Among authors: henske ep. Cell Cycle. 2009 Dec 15;8(24):4168-75. doi: 10.4161/cc.8.24.10800. Cell Cycle. 2009. PMID: 20054236 Free PMC article.

8

Estrogen-induced activation of mammalian target of rapamycin is mediated via tuberin and the small GTPase Ras homologue enriched in brain.

Yu J, Henske EP. Yu J, et al. Among authors: henske ep. Cancer Res. 2006 Oct 1;66(19):9461-6. doi: 10.1158/0008-5472.CAN-06-1895. Cancer Res. 2006. PMID: 17018601

9

mTOR is activated in the majority of malignant melanomas.

Karbowniczek M, Spittle CS, Morrison T, Wu H, Henske EP. Karbowniczek M, et al. Among authors: henske ep. J Invest Dermatol. 2008 Apr;128(4):980-7. doi: 10.1038/sj.jid.5701074. Epub 2007 Oct 4. J Invest Dermatol. 2008. PMID: 17914450 Free article.

10

Activation of the mTOR signaling pathway in renal clear cell carcinoma.

Robb VA, Karbowniczek M, Klein-Szanto AJ, Henske EP. Robb VA, et al. Among authors: henske ep. J Urol. 2007 Jan;177(1):346-52. doi: 10.1016/j.juro.2006.08.076. J Urol. 2007. PMID: 17162089

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