Michnick SW - Search Results

1

Universal strategies in research and drug discovery based on protein-fragment complementation assays.

Michnick SW, Ear PH, Manderson EN, Remy I, Stefan E. Michnick SW, et al. Nat Rev Drug Discov. 2007 Jul;6(7):569-82. doi: 10.1038/nrd2311. Nat Rev Drug Discov. 2007. PMID: 17599086 Review.

2

A cDNA library functional screening strategy based on fluorescent protein complementation assays to identify novel components of signaling pathways.

Remy I, Michnick SW. Remy I, et al. Among authors: michnick sw. Methods. 2004 Apr;32(4):381-8. doi: 10.1016/j.ymeth.2003.10.011. Methods. 2004. PMID: 15003600

3

Mapping biochemical networks with protein-fragment complementation assays.

Remy I, Michnick SW. Remy I, et al. Among authors: michnick sw. Methods Mol Biol. 2004;261:411-26. doi: 10.1385/1-59259-762-9:411. Methods Mol Biol. 2004. PMID: 15064473 Review.

4

A highly sensitive protein-protein interaction assay based on Gaussia luciferase.

Remy I, Michnick SW. Remy I, et al. Among authors: michnick sw. Nat Methods. 2006 Dec;3(12):977-9. doi: 10.1038/nmeth979. Epub 2006 Nov 12. Nat Methods. 2006. PMID: 17099704

5

Application of protein-fragment complementation assays in cell biology.

Remy I, Michnick SW. Remy I, et al. Among authors: michnick sw. Biotechniques. 2007 Feb;42(2):137, 139, 141 passim. doi: 10.2144/000112396. Biotechniques. 2007. PMID: 17373475 Free article.

6

Detection of protein-protein interactions using a simple survival protein-fragment complementation assay based on the enzyme dihydrofolate reductase.

Remy I, Campbell-Valois FX, Michnick SW. Remy I, et al. Among authors: michnick sw. Nat Protoc. 2007;2(9):2120-5. doi: 10.1038/nprot.2007.266. Nat Protoc. 2007. PMID: 17853867

7

Using the beta-lactamase protein-fragment complementation assay to probe dynamic protein-protein interactions.

Remy I, Ghaddar G, Michnick SW. Remy I, et al. Among authors: michnick sw. Nat Protoc. 2007;2(9):2302-6. doi: 10.1038/nprot.2007.356. Nat Protoc. 2007. PMID: 17853887

8

A general life-death selection strategy for dissecting protein functions.

Ear PH, Michnick SW. Ear PH, et al. Among authors: michnick sw. Nat Methods. 2009 Nov;6(11):813-6. doi: 10.1038/nmeth.1389. Epub 2009 Oct 11. Nat Methods. 2009. PMID: 19820714

9

A toolkit of protein-fragment complementation assays for studying and dissecting large-scale and dynamic protein-protein interactions in living cells.

Michnick SW, Ear PH, Landry C, Malleshaiah MK, Messier V. Michnick SW, et al. Methods Enzymol. 2010;470:335-68. doi: 10.1016/S0076-6879(10)70014-8. Epub 2010 Mar 1. Methods Enzymol. 2010. PMID: 20946817

10

Protein-fragment complementation assays for large-scale analysis, functional dissection and dynamic studies of protein-protein interactions in living cells.

Michnick SW, Ear PH, Landry C, Malleshaiah MK, Messier V. Michnick SW, et al. Methods Mol Biol. 2011;756:395-425. doi: 10.1007/978-1-61779-160-4_25. Methods Mol Biol. 2011. PMID: 21870242

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