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Identification of Cys385 in the isolated kinase insertion domain of heme-regulated eIF2 alpha kinase (HRI) as the heme axial ligand by site-directed mutagenesis and spectral characterization.
Hirai K, Martinkova M, Igarashi J, Saiful I, Yamauchi S, El-Mashtoly S, Kitagawa T, Shimizu T. Hirai K, et al. Among authors: shimizu t. J Inorg Biochem. 2007 Aug;101(8):1172-9. doi: 10.1016/j.jinorgbio.2007.05.004. Epub 2007 May 24. J Inorg Biochem. 2007. PMID: 17597215
Binding of oxygen and carbon monoxide to a heme-regulated phosphodiesterase from Escherichia coli. Kinetics and infrared spectra of the full-length wild-type enzyme, isolated PAS domain, and Met-95 mutants.
Taguchi S, Matsui T, Igarashi J, Sasakura Y, Araki Y, Ito O, Sugiyama S, Sagami I, Shimizu T. Taguchi S, et al. Among authors: shimizu t. J Biol Chem. 2004 Jan 30;279(5):3340-7. doi: 10.1074/jbc.M301013200. Epub 2003 Nov 11. J Biol Chem. 2004. PMID: 14612459 Free article.
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