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Immunogenicity and protection of a variant nanoparticle vaccine that confers broad neutralization against SARS-CoV-2 variants.
Logue J, Johnson RM, Patel N, Zhou B, Maciejewski S, Foreman B, Zhou H, Portnoff AD, Tian JH, Rehman A, McGrath ME, Haupt RE, Weston SM, Baracco L, Hammond H, Guebre-Xabier M, Dillen C, Madhangi M, Greene AM, Massare MJ, Glenn GM, Smith G, Frieman MB. Logue J, et al. Among authors: frieman mb. Nat Commun. 2023 Feb 28;14(1):1130. doi: 10.1038/s41467-022-35606-6. Nat Commun. 2023. PMID: 36854666 Free PMC article.
Exhaled Breath Aerosol Shedding of Highly Transmissible Versus Prior Severe Acute Respiratory Syndrome Coronavirus 2 Variants.
Lai J, Coleman KK, Tai SHS, German J, Hong F, Albert B, Esparza Y, Srikakulapu AK, Schanz M, Maldonado IS, Oertel M, Fadul N, Gold TL, Weston S, Mullins K, McPhaul KM, Frieman M, Milton DK. Lai J, et al. Among authors: frieman m. Clin Infect Dis. 2023 Mar 4;76(5):786-794. doi: 10.1093/cid/ciac846. Clin Infect Dis. 2023. PMID: 36285523 Free PMC article.
Systematic functional interrogation of SARS-CoV-2 host factors using Perturb-seq.
Sunshine S, Puschnik AS, Replogle JM, Laurie MT, Liu J, Zha BS, Nuñez JK, Byrum JR, McMorrow AH, Frieman MB, Winkler J, Qiu X, Rosenberg OS, Leonetti MD, Ye CJ, Weissman JS, DeRisi JL, Hein MY. Sunshine S, et al. Among authors: frieman mb. Nat Commun. 2023 Oct 6;14(1):6245. doi: 10.1038/s41467-023-41788-4. Nat Commun. 2023. PMID: 37803001 Free PMC article.
SARS-CoV-2 Variant Spike and accessory gene mutations alter pathogenesis.
McGrath ME, Xue Y, Dillen C, Oldfield L, Assad-Garcia N, Zaveri J, Singh N, Baracco L, Taylor L, Vashee S, Frieman M. McGrath ME, et al. Among authors: frieman m. bioRxiv [Preprint]. 2022 Jun 1:2022.05.31.494211. doi: 10.1101/2022.05.31.494211. bioRxiv. 2022. Update in: Proc Natl Acad Sci U S A. 2022 Sep 13;119(37):e2204717119. doi: 10.1073/pnas.2204717119 PMID: 35677080 Free PMC article. Updated. Preprint.
A neonatal mouse model characterizes transmissibility of SARS-CoV-2 variants and reveals a role for ORF8.
Rodriguez-Rodriguez BA, Ciabattoni GO, Duerr R, Valero-Jimenez AM, Yeung ST, Crosse KM, Schinlever AR, Bernard-Raichon L, Rodriguez Galvan J, McGrath ME, Vashee S, Xue Y, Loomis CA, Khanna KM, Cadwell K, Desvignes L, Frieman MB, Ortigoza MB, Dittmann M. Rodriguez-Rodriguez BA, et al. Among authors: frieman mb. Nat Commun. 2023 May 25;14(1):3026. doi: 10.1038/s41467-023-38783-0. Nat Commun. 2023. PMID: 37230979 Free PMC article.
Carbohydrate fatty acid monosulphate: oil-in-water adjuvant enhances SARS-CoV-2 RBD nanoparticle-induced immunogenicity and protection in mice.
Nanishi E, Borriello F, Seo HS, O'Meara TR, McGrath ME, Saito Y, Chen J, Diray-Arce J, Song K, Xu AZ, Barman S, Menon M, Dong D, Caradonna TM, Feldman J, Hauser BM, Schmidt AG, Baden LR, Ernst RK, Dillen C, Yu J, Chang A, Hilgers L, Platenburg PP, Dhe-Paganon S, Barouch DH, Ozonoff A, Zanoni I, Frieman MB, Dowling DJ, Levy O. Nanishi E, et al. Among authors: frieman mb. NPJ Vaccines. 2023 Feb 14;8(1):18. doi: 10.1038/s41541-023-00610-4. NPJ Vaccines. 2023. PMID: 36788219 Free PMC article.
169 results